Analysis of clinical features of 1800 inpatients with thrombocytopenia in our hospital
Objective To investigate the department distribution and etiology of inpatients with thrombocytopenia in Shenzhen Hospital of Southern Medical University,and to provide reference for clinical diagnosis and treatment.Methods The clinical data of 1800 patients with thrombocytopenia were collected from the hospital information system(HIS),and the age,gender,etiology,department distribution and degree of thrombocytopenia of the patients were analyzed retrospectively.Results The median age of 1800 patients with thrombocytopenia was 56 years old(1 d-98 years old),of which 1062 patients were≤60 years old,accounting for 59.00%;738 patients were>60 year old patients,accounting for 41.00%.Among the 1800 patients,993 cases were males,accounting for 55.17%;807 cases were female,accounting for 44.83%.The median platelet count was 80×109/L in male patients and 80×109/L in female patients.Among 1800 patients,121 cases(6.72%)had platelet count≤20×109/L,274 cases(15.22%)had platelet count(20-50)×109/L;1405 cases(78.06%)had platelet count(51-100)×109/L.1800 patients with thrombocytopenia were mainly distributed in department of hematology,hepatology,intensive care medicine,oncology,general surgery and other departments,among which hematology accounted for 19.39%,and the median platelet count was 50×109/L.There were 399 cases of thrombocytopenia caused by diseases of the blood system,accounting for 22.17%;346 cases of liver disease,accounting for 19.22%;300 cases of tumor,accounting for 16.67%;297 cases of infectious diseases,accounting for 16.50%;134 cases of cardiovascular and cerebrovascular diseases,accounting for 7.44%;78 cases of kidney disease,accounting for 4.33%;41 cases of thrombocytopenia during pregnancy,accounting for 2.28%;27 cases of endocrine diseases,accounting for 1.50%and 178 cases of other diseases,accounting for 9.89%.The mean platelet count for blood system diseases was 50.58×109/L,the mean platelet count for liver diseases was 72.93×109/L,the mean platelet count for endocrine diseases was 74.56×109/L,the mean platelet count for tumor patients was 75.10×109/L,the mean platelet count for cardiovascular and cerebrovascular diseases was 75.73×109/L,the mean platelet count for kidney diseases was 77.01×109/L,the mean platelet count for infectious diseases was 78.05×109/L,and the mean platelet count for other diseases was 80.65×109/L,the mean platelet count for thrombocytopenia during pregnancy was 83.10×109/L.The mean platelet count of patients with blood system diseases was the lowest,and the difference was statistically significant compared with the other 8 diseases(P<0.001).The mean platelet count of patients with liver disease was significantly different from that of patients with other diseases(P<0.01),while there was no statistically statistical significance in pair-to-pair comparison of patients with other diseases(P>0.05).Conclusion The main diseases of inpatients with thrombocytopenia in 2021 are blood system diseases,liver diseases,tumors and infectious diseases.Among them,thrombocytopenia in patients with blood system diseases is the most serious,which needs clinical attention,and thrombocytopenia caused by other system diseases also needs clinical attention.
NETL
NSTL
万方数据
维普
