Analysis of the influence of Xuebijing combined with sputum aspiration and lavage by fiberbronchoscope on blood gas indexes and inflammatory factors in patients with severe pneumonia
Objective To analyze the effects of Xuebijing combined with sputum aspiration and lavage by fiberbronchoscope on blood gas indexes and inflammatory factors in patients with severe pneumonia.Methods 94 patients with severe pneumonia were randomly divided into conventional group and combined group according to random numerical table,with 47 cases in each group.The conventional group was given sputum aspiration and lavage by fiberbronchoscope,and the combined group was treated with Xuebijing based on the conventional group.Comparison was made on symptom remission time,blood gas index[arterial partial pressure of oxygen(PaO2),blood oxygen saturation(SaO2),arterial partial pressure of carbon dioxide(PaCO2)],inflammatory factors[tumor necrosis factor-α(TNF-α),procalcitonin(PCT),C-reactive protein(CRP)]levels.Results The combined group had antipyretic time of(4.30±1.09)d,asthmatic disappearance time of(4.21±1.26)d and lung rale disappearance time of(5.27±1.25)d,which were shorter than those of(7.76±1.35),(6.01±1.20)and(9.86±1.31)d in the conventional group,and the data was different(P<0.05).After treatment,PaO2 of(83.51±6.42)mm Hg(1 mm Hg=0.133 kPa)and SaO2 of(92.19±6.72)％in the combined group were higher than those of(74.49±5.36)mm Hg and(84.49±6.37)％in the conventional group,while PaCO2 of(42.75±6.43)mm Hg was lower than that of(47.62±3.09)mm Hg in the conventional group,and the data were different(P<0.05).After treatment,the combined group had TNF-α of(51.47±6.81)ng/L,PCT of(0.62±0.13)ng/ml,CRP of(24.62±3.61)mg/L,which were lower than those of(66.55±7.16)ng/L,(1.39±0.24)ng/ml,(41.50±5.77)mg/L in the conventional group.The data was different(P<0.05).Conclusion The application of Xuebijing plus bronchoscopy for sputum aspiration and lavage in patients with severe pneumonia has good effect.It can reduce the time of symptom disappearance,and promote the improvement of the level of blood gas indexes and inflammatory factors,which is worthy of clinical promotion.
XuebijingSputum aspiration and lavage by fiberbronchoscopeSevere pneumoniaBlood gas indexInflammatory factor
万方数据
维普
