Clinical effect analysis of Qianlie Shutong combined with tamsulosin hydrochloride in the treatment of chronic nonbacterial prostatitis
Objective To analyze the clinical effect of Qianlie Shutong combined with tamsulosin hydrochloride in the treatment of chronic nonbacterial prostatitis.Methods A total of 82 patients with chronic nonbacterial prostatitis were divided into a normal group and a research group according to random number table method,with 41 cases in each group.Patients in the normal group were treated with Qianlie Shutong alone,and patients in the research group were treated with Qianlie Shutong combined with tamsulosin hydrochloride.Comparison was made on National Institutes of Health Chronic Prostatitis Symptom Index(NIH-CPSI)score,proinflammatory factors[white blood cell count(WBC),interleukin-1β(IL-1β),interleukin-8(IL-8),tumor necrosis factor-α(TNF-α)]levels,urination indicators after treatment,and clinical effect between the two groups.Results After treatment,the scores of urination symptoms,pain symptoms,severity,quality of life and total score in the research group were(3.53±0.60),(6.24±1.12),(9.77±2.05),(6.21±1.02)and(15.98±2.66)points,which were lower than(4.87±0.92),(9.67±1.21),(14.54±2.39),(8.98±1.26)and(23.52±3.82)points in the normal group,and there was statistical difference between groups(P<0.05).After treatment,the number of urgent urination,the maximum urine flow,the number of nocturnal urination and the number of urination in the research group were(2.52±0.21)times/d,(17.18±2.45)ml/s,(1.83±0.28)times/night and(6.32±1.41)times/d,which were lower than(5.09±0.87)times/d,(21.43±3.36)ml/s,(3.31±0.56)times/night,and(10.24±2.17)times/d in the normal group,and there was statistical difference between groups(P<0.05).After treatment,the levels of WBC,IL-1β,IL-8 and TNF-α in the research group were(10.35±1.08)/HP,(54.73±10.04)pg/ml,(5.73±0.98)ng/ml and(42.34±8.01)ng/ml,which were lower than(12.64±1.73)/HP,(68.25±10.71)pg/ml,(7.85±1.04)ng/ml,(57.02±8.23)ng/ml in the normal group,and there were statistical differences between groups(P<0.05).The total clinical effective rate of 92.68%in the research group was higher than 73.17%in the normal group,and there were statistical differences between groups(P<0.05).Conclusion For patients with chronic nonbacterial prostatitis,the combination of Qianlie Shutong and tamsulosin hydrochloride can significantly improve their symptoms and urination indicators,shorten the recovery time,and have a good clinical effect.
万方数据
维普
