Analysis of curative effect of laparoscopic radical resection for colon cancer and its influence on gastrointestinal function
Objective To explore the clinical effect of laparoscopic radical resection for colon cancer and its influence on gastrointestinal function.Methods 58 patients with colon cancer were randomly divided into a control group and a study group with 29 cases in each group.The control group was treated with traditional open surgery,and the study group was treated with laparoscopic radical resection of colon cancer.The perioperative related indicators,number of lymph node dissection,serum inflammatory indicators,serum stress indicators and complication rate were compared between the two groups.Results The intraoperative blood loss of(87.63±6.24)ml and postoperative drainage volume of(24.32±2.05)ml in the study group were less than(122.25±9.52)and(30.23±2.63)ml in the control group;the study group had operation time of(136.15±7.16)min,postoperative exhaust time of(3.14±0.26)d,bowel sound recovery time of(2.34±0.43)d,diet recovery time of(68.74±4.23)h,hospitalization time of(10.42±1.16)d,which were shorter than(141.05±8.75)min,(4.25±0.55)d,(3.58±0.75)d,(87.36±5.52)h,(15.27±1.44)d in the control group(P<0.05).There was no significant difference in the number of lymph node dissection in patients with stage Ⅰ and Ⅱ tumors between the two groups(P>0.05).The number of lymph node dissection,the number of positive lymph node dissection,the number of left hemicolonic lymph node dissection,and the number of right hemicolonic lymph node dissection in patients with stage Ⅲ tumor in the study group were(25.11±2.02),(21.06±2.14),(18.87±1.42),and(24.23±2.14)nodes,which were more than(17.58±1.36),(12.25±1.23),(16.25±1.26),and(18.54±1.52)nodes in the control group(P<0.05).After surgery,the control group had interleukin-6(IL-6)of(28.85±2.12)pg/ml and C-reactive protein(CRP)of(12.36±1.42)mg/L,and the study group had IL-6 of(17.96±1.63)pg/ml and CRP of(8.64±1.15)mg/L.The levels of IL-6 and CRP in the study group were lower than those in the control group(P<0.05).After surgery,the epinephrine of the control group was(99.87±7.58)pg/ml,the norepinephrine was(176.52±9.36)pg/ml and the cortisol was(24.63±2.14)pg/ml;the epinephrine of the study group was(64.25±4.31)pg/ml,the norepinephrine was(87.56±5.15)pg/ml and the cortisol was(13.54±1.63)pg/ml.The levels of epinephrine,norepinephrine and cortisol in both groups increased,and the study group were higher than the control group(P<0.05).The incidence of complications in the study group was 6.90%,which was lower than 31.03%that in the control group(P<0.05).Conclusion In the treatment of colon cancer,laparoscopic radical resection of colon cancer can increase the number of lymph node dissection,shorten the recovery time of postoperative gastrointestinal function,improve the levels of serum inflammatory indicators and stress response,and reduce postoperative complications,which is conducive to postoperative rehabilitation of the body,so it is recommended to be widely used in clinic.
Colon cancerLaparoscopic radical resection for colon cancerNumber of lymph node dissectionGastrointestinal functionSerum indexComplications
万方数据
维普
