Diagnostic value of prostatic fluid immunoglobulin measurements in chronic prostatitis
Objective To explore the diagnostic value of prostatic fluid immunoglobulin measurements in chronic prostatitis.Methods A total of 300 patients with chronic prostatitis(observation group)and 100 healthy subjects(control group)were selected for the study.Both groups received prostatic fluid immunoglobulin measurement[immunoglobulin A(IgA),immunoglobulin M(IgM),immunoglobulin G(IgG)].Comparison was made on measurement results of two groups,and the measurement results of patients with different pathological subtypes(type Ⅱ,type ⅢA,type ⅢB),and different disease severity(mild,moderate,and severe)in the observation group.Results The levels of IgA,IgM and IgG in the observation group were(2.96±0.41),(2.92±0.38)and(9.04±2.02)g/L,which were higher than(0.48±0.14),(0.38±0.11)and(2.39±0.30)g/L in the control group(P<0.05).There were no significant differences in IgA,IgM and IgG in patients with type Ⅱ,typeⅢA and type ⅢB in the observation group(P>0.05).There were statistically significant differences in IgA,IgM and IgG among patients with different disease severity in the observation group(P<0.05).With the aggravation of the disease,the level of prostatic fluid immunoglobulin in the observation group was increased(P<0.05).Conclusion Compared with healthy subjects,patients with chronic prostatitis have obvious elevated prostatic fluid immunoglobulin content,and there are obvious differences in patients with different disease severity.The more serious the disease,the higher the level of prostatic fluid immunoglobulin.Therefore,the determination of prostatic fluid immunoglobulin in patients with chronic prostatitis can be strengthened clinically,which not only has a guiding effect on diagnosis,but also can judge the severity of the disease.
Chronic prostatitisProstatic fluidImmunoglobulinPathological subtypesDisease severityDiagnostic value