Objective To analyze the clinical efficacy of different doses of glucocorticoid pulse therapy in patients with rheumatism.Methods 80 patients with rheumatism were randomly divided into a control group and a study group,each with 40 cases.The control group received low-dose methylprednisolone sodium succinate treatment,and the study group received high-dose methylprednisolone sodium succinate treatment.The treatment effect and occurrence of adverse reactions were compared between the two groups.Results The total effective rate of treatment in the study group was 90.0%,which was higher than 60.0%in the control group,and there was a significant difference in comparison(P<0.05).The incidence of adverse reactions during treatment in the study group was 37.5%,and there was no significant difference compared to the control group's 25.0%(P>0.05).Conclusion High-dose glucocorticoid pulse therapy for patients with rheumatism can improve the clinical efficacy of the disease without causing serious adverse reactions.
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