首页|不同剂量糖皮质激素冲击治疗风湿病患者的临床疗效分析

不同剂量糖皮质激素冲击治疗风湿病患者的临床疗效分析

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目的 分析不同剂量糖皮质激素冲击治疗风湿病的临床疗效.方法 80 例风湿病患者,采取随机形式分为对照组和研究组,每组 40 例.对照组接受小剂量甲泼尼龙琥珀酸钠治疗,研究组接受大剂量甲泼尼龙琥珀酸钠治疗.比较两组患者治疗效果、不良反应发生情况.结果 研究组疾病治疗总有效率 90.0%高于对照组的 60.0%,对比存在显著差异(P<0.05).研究组治疗期间不良反应发生率为 37.5%,与对照组的 25.0%对比不存在显著差异(P>0.05).结论 临床中为风湿病患者提供大剂量糖皮质激素进行冲击治疗,能够提高疾病临床疗效,且不会引发严重不良反应.
Analysis of clinical efficacy of different doses of glucocorticoid pulse therapy in patients with rheumatism
Objective To analyze the clinical efficacy of different doses of glucocorticoid pulse therapy in patients with rheumatism.Methods 80 patients with rheumatism were randomly divided into a control group and a study group,each with 40 cases.The control group received low-dose methylprednisolone sodium succinate treatment,and the study group received high-dose methylprednisolone sodium succinate treatment.The treatment effect and occurrence of adverse reactions were compared between the two groups.Results The total effective rate of treatment in the study group was 90.0%,which was higher than 60.0%in the control group,and there was a significant difference in comparison(P<0.05).The incidence of adverse reactions during treatment in the study group was 37.5%,and there was no significant difference compared to the control group's 25.0%(P>0.05).Conclusion High-dose glucocorticoid pulse therapy for patients with rheumatism can improve the clinical efficacy of the disease without causing serious adverse reactions.

RheumatismGlucocorticoidPulse therapyDifferent dosesClinical efficacyAdverse reactions

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628000 广元市中心医院全科医学科

风湿病 糖皮质激素 冲击治疗 不同剂量 临床疗效 不良反应

2024

中国实用医药
中国康复医学会

中国实用医药

影响因子:0.797
ISSN:1673-7555
年,卷(期):2024.19(4)
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