Effect analysis of systemic antibiotic therapy and periodontal local treatment for adolescent patients with periodontitis
Objective To explore the effect of systemic antibiotic therapy and periodontal local treatment for adolescent patients with periodontitis.Methods 52 adolescent patients with periodontitis were selected as the subjects of this study,and divided into a reference group(n=26)and an observation group(n=26)according to different treatment plans.The reference group received local treatment of periodontitis with conventional drugs,and the observation group received systemic antibiotic therapy on the basis of the reference group.The total effective rate of disease treatment,recovery time,changes of periodontal indexes before and after treatment,and changes of inflammatory indexes of periodontitis before and after treatment were compared between the two groups.Results The total effective rate of disease treatment was 96.15%in the observation group,which was higher than 76.92%in the reference group(P<0.05).The observation group had inflammatory absorption time of(5.03±2.01)d and pain disappearance time of(7.05±0.69)d,which were shorter than(6.23±1.98)and(8.26±1.02)d in the reference group(P<0.05).After treatment,the bleeding index,clinical attachment level,plaque index and periodontal probing depth of patients in both groups were significantly improved compared with those before treatment,and the comparison between groups showed that the bleeding index,clinical attachment level,plaque index and periodontal probing depth of patients in the observation group were lower than those in the reference group(P<0.05).After treatment,the serum procalcitonin and hypersensitive C-reactive protein were significantly improved in both groups compared with before treatment,and inter-group comparison showed that the serum calcitonin and hypersensitive C-reactive protein in the observation group were lower than those in the reference group(P<0.05).Conclusion Systemic antibiotic therapy and periodontal local treatment for adolescent patients with periodontitis can improve the total effective rate of disease treatment,promote disease recovery,and improve the gingival condition and inflammation of patients,which has positive clinical value.
Periodontitis in adolescentSystemic antibiotic therapyPeriodontal local treatmentGingival statusInflammatory condition
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