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高敏心肌肌钙蛋白升高的临床意义

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心肌肌钙蛋白是急性心肌梗死的经典诊断标志物.随着检测技术的不断发展,心肌肌钙蛋白检测的敏感性显著提升,高敏心肌肌钙蛋白(hs-cTn)已在国内被广泛应用,为急性心血管事件的早期诊断和预后分层提供了良好的实验室依据.在心脏相关疾病以外的某些疾病也可检测到hs-cTn,某些生理因素下也可能导致心肌肌钙蛋白释放入血从而被检出.阐明hs-cTn升高的可能原因及机制具有重要的理论价值和实际意义,有助于临床医生的临床决策,使患者得到及时、合理的治疗.
Clinical significance of high sensitive cardiac troponin elevation
Myocardial troponin is a classic diagnostic biomarker for acute myocardial infarction.With the continuous development of detection technology,the sensitivity of cardiac troponin detection has been significantly improved,and high sensitive cardiac troponin(hs-cTn)has been widely used,providing a good laboratory basis for the early diagnosis and prognosis stratification for patients with acute cardiovascular events.Hs-cTn can also be detected in some diseases other than heart-related diseases,and some physiological factors may cause the release of cardiac troponin.It is of great theoretical and practical significance to elucidate the possible causes and mechanisms of high sensitive cardiac troponin elevation,which is helpful for clinical doctors to make appropriate decisions and enable patients to get timely and reasonable treatment.

High sensitive cardiac troponinMechanismsMyocardial injuryDifferential diagnosis

王童、明秀芬

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100034 北京大学第一医院检验科

高敏心肌肌钙蛋白 机制 心肌损伤 鉴别诊断

2024

中国实用医药
中国康复医学会

中国实用医药

影响因子:0.797
ISSN:1673-7555
年,卷(期):2024.19(4)
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