Clinical Efficacy of Lipoic Acid Capsules Combined with Mecobalamin Tablets in the Treatment of Diabetic Peripheral Neuropathy
Objective To analyze the clinical efficacy of treating diabetic peripheral neuropathy(DPN)patients with a combination of lipoic acid capsules and mecobalamin tablets beyond the use of mecobalamin alone.Methods This study involved 80 patients with diabetic peripheral neuropathy.Using a random number method,they were divided into an observation group and a control group,with 40 patients in each.The control group was treated exclusively with mecobalamin tablets,while the observation group received a combination treatment of lipoic acid capsules and mecobalamin tablets.The clinical efficacy,motor nerve conduction velocity(MNCV),sensory nerve conduction velocity(SNCV),and the scores from the Toronto Clinical Scoring System(TCSS)were compared between the two groups.Results Compared to the control group,the observation group showed a significantly higher overall effective rate(P<0.05).After treatment,there was an improvement in MNCV and SNCV in the observation group as compared to the control group(P<0.05).Furthermore,following the treatment,the TCSS scores of patients in the observation group were lower than those in the control group(P<0.05).Conclusion The adjuvant treatment with lipoic acid capsules to mecobalamin tablets can improve motor and sensory nerve conduction velocity,slow the progression of the disease,and enhance the therapeutic effect.This approach is worthy of clinical reference and promotion.
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