Analysis of the correlation of the blood flow indexes of fetal middle cerebral artery and umbilical artery with the results of umbilical cord blood gas analysis
Objective To analyze the correlation of the blood flow indexes of fetal middle cerebral artery and umbilical artery with the results of umbilical cord blood gas analysis.Methods 90 pregnant women were selected and divided into a control group(no fetal distress,74 cases)and an observation group(fetal distress,16 cases)according to whether there was fetal distress.Routine ultrasound examination was performed in the third trimester of pregnancy and umbilical cord blood gas analysis was performed after birth.Comparison was made on blood flow indexes[diastolic velocity(VD),systolic velocity(VS),pulsation index(PI),resistance index(RI)and the ratio of peak systolic velocity to end-diastolic velocity(S/D)]of fetal middle cerebral artery and umbilical artery were compared between the two groups,as well as the blood gas index[partial pressure of carbon dioxide(PCO2),partial pressure of oxygen(PO2),base excess(BE),pH value]of fetal cord blood.The correlation of the blood flow indexes of fetal middle cerebral artery and umbilical artery with the results of umbilical cord blood gas analysis was analyzed.Results In the control group,the values of VD,VS,PI,RI and S/D of middle cerebral artery were(20.17±2.01)cm/s,(68.31±2.39)cm/s,(1.48±0.28),(0.74±0.18)and(4.45±0.74),and those of umbilical artery were(16.64±4.25)cm/s,(61.02±4.21)cm/s,(0.74±0.21),(0.59±0.10)and(3.24±0.72).In the observation group,the values of VD,VS,PI,RI and S/D of middle cerebral artery were(15.04±2.03)cm/s,(66.25±2.37)cm/s,(1.25±0.31),(0.55±0.14)and(3.22±0.85),and those of umbilical artery were(12.25±3.89)cm/s,(57.26±4.30)cm/s,(1.02±0.20),(0.75±0.14)and(2.25±0.64).Compared with the control group,the values of VD,VS,PI,RI and S/D of fetal middle cerebral artery in the observation group were lower;VD,VS and SD of umbilical artery were lower,while the values of PI and RI were higher(P<0.05).The observation group had fetal pH of(7.15±0.03),PO2 of(23.24±4.29)mm Hg(1 mm Hg= 0.133 kPa)and BE of(-7.24±1.41)mmol/L,which were lower than(7.26±0.02)and(28.11±4.36)mm Hg and(-6.01±1.45)mmol/L in the control group;the observation group had higher PCO2 of(61.33±2.37)mm Hg than(45.35±2.31)mm Hg in the control group(P<0.05).The values of VD,VS,PI,RI and SD of fetal middle cerebral artery were positively correlated with pH,PO2 and BE of umbilical artery,and negatively correlated with PCO2 of umbilical artery(P<0.05).The value of VD,VS and SD of fetal umbilical artery were positively correlated with pH,PO2 and BE,and negatively correlated with PCO2(P<0.05).The value of PI and RI of umbilical artery were negatively correlated with pH,PO2 and BE,and positively correlated with PCO2(P<0.05).Fetal middle cerebral artery blood flow index was positively correlated with umbilical cord blood pH,PO2,BE,and negatively correlated with PCO2(P<0.05).Fetal umbilical artery blood flow indexes VD,VS and SD were positively correlated with pH,PO2 and BE,and negatively correlated with PCO2(P<0.05).Umbilical artery blood flow indexes PI and RI were negatively correlated with pH,PO2 and BE,and positively correlated with PCO2(P<0.05).Conclusion There is a correlation between the blood flow indexes of fetal middle cerebral artery and umbilical artery and the results of umbilical cord blood gas analysis.Clarifying the blood flow indexes of fetal arteries and the results of mbilical cord blood gas analysis can provide guidance for clinical evaluation of fetal distress.
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