Analysis of the value of alanine aminotransferase detection in blood screening
Objective To study the important role of alanine aminotransferase(ALT)in blood screening.Methods 90 blood specimens from unpaid donors were collected.According to the different results of alanine aminotransferase detection,10 positive specimens(>50 U/L)were set as the observation group,and 80 negative specimens(≤50 U/L)were set as the control group.Blood screening was performed in both groups.The distribution of alanine aminotransferase in 90 blood specimens were observed,and the positive rates of hepatitis C virus(HCV)and hepatitis B virus surface antigen(HBsAg)were compared between the observation group and the control group.Results In 90 blood specimens from unpaid donors,alanine aminotransferase levels were mostly≤20 U/L in HBsAg-positive as well as anti-hepatitis C virus(anti-HCV)positive cases;positive nucleic acid testing(NAT)associations were identified as negative,and alanine aminotransferase levels were mostly≤50 U/L.The positive rates of HCV and HBsAg in the observation group were 40.00%and 60.00%,which were higher than 33.75%and 53.75%in the control group,but the differences were not statistically significant(P>0.05).Conclusion During the period of comprehensive blood screening for blood specimens collected from blood stations,the safety of blood testing has also shown a certain trend of improvement in the context of the increasing importance of blood screening.However,the detection value of alanine aminotransferase is relatively limited,so in addition to the detection of alanine aminotransferase,the detection of the five indicators of blood transfusion and other indicators in blood screening should also be done well,so as to provide more evidence for clinical practice and screen out abnormal blood specimens in time.
Blood screeningAlanine aminotransferaseDetectionBlood station
NETL
NSTL
万方数据
维普
