首页|苏黄止咳胶囊对风热犯肺型社区获得性肺炎患者证候积分和炎症指标的影响

苏黄止咳胶囊对风热犯肺型社区获得性肺炎患者证候积分和炎症指标的影响

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目的 探讨风热犯肺型社区获得性肺炎(CAP)采用苏黄止咳胶囊治疗对患者证候积分、炎症指标的影响.方法 80 例风热犯肺型CAP患者,随机分为观察组与对照组,每组 40 例.对照组采用西医治疗,观察组在对照组基础上行苏黄止咳胶囊治疗.比较两组患者治疗前后证候积分、炎症指标、治疗效果、用药安全性.结果 治疗后,两组患者主症、次症积分及总分均低于治疗前,且观察组主症、次症积分及总分分别为(6.42±1.38)、(3.08±0.84)、(9.50±1.48)分,低于对照组的(8.48±2.81)、(4.76±1.07)、(13.24±2.63)分,差异均有统计学意义(P<0.05).治疗后,两组患者白细胞计数(WBC)、中性粒细胞(NE)、C反应蛋白(CRP)、降钙素原(PCT)均较治疗前改善,且观察组WBC、NE、CRP、PCT分别为(4.81±0.94)×109/L、(63.18±5.22)%、(7.52±1.11)mg/L、(0.17±0.05)ng/ml,低于对照组的(6.86±0.57)×109/L、(67.86±5.57)%、(9.47±1.85)mg/L、(0.34±0.06)ng/ml,差异均有统计学意义(P<0.05).观察组治疗总有效率为 97.50%,高于对照组的 82.50%,差异有统计学意义(P<0.05).两组患者在用药期间均未出现过敏等不良反应.结论 苏黄止咳胶囊可从中医理论出发作用于风热犯肺型CAP患者的病因病机,调控机体炎症状态,改善疾病症状,提升治疗效果,且具有用药安全性,值得推广.
Effect of Suhuang Zhike Capsule on syndrome score and inflammatory indicators of patients with community-acquired pneumonia with wind-heat invading lung syndrome
Objective To explore the effect of Suhuang Zhike Capsule on syndrome score and inflammatory indicators of patients with community-acquired pneumonia(CAP)with wind-heat invading lung syndrome.Methods 80 cases of CAP with wind-heat invading lung syndrome were randomly divided into an observation group and a control group,with 40 cases in each group.The control group was treated with Western medicine,and the observation group was treated with Suhuang Zhike Capsule on the basis of the control group.The syndrome score and inflammatory indicators before and after treatment,therapeutic effect and drug safety were compared between the two groups.Results After treatment,the scores of main symptoms,secondary symptoms and total score of the two groups were lower than those before treatment;the scores of main symptoms,secondary symptoms and total score of the observation group were(6.42±1.38),(3.08±0.84)and(9.38±1.48)points,which were lower than(8.48±2.81),(4.76±1.07)and(13.24±2.63)points of the control group;the differences were statistically significant(P<0.05).After treatment,the white blood cell count(WBC),neutrophils(NE),C-reactive protein(CRP)and procalcitonin(PCT)in both groups were improved compared with those before treatment;WBC,NE,CRP and PCT were(4.81±0.94)×109/L,(63.18±5.22)%,(7.52±1.11)mg/L and(0.17±0.05)ng/ml in the observation group,which were lower than(4.86±0.57)×109/L,(67.86±5.57)%,(9.47±1.85)mg/L and(0.34±0.06)ng/ml in the control group;the difference was statistically significant(P<0.05).The total effective rate of the observation group was 97.50%,which was higher than 82.50%of the control group,and the difference was statistically significant(P<0.05).No adverse reactions of allergy occurred in both groups during the treatment period.Conclusion Based on the theory of traditional Chinese medicine,Suhuang Zhike Capsule can act on the etiology and pathogenesis of CAP patients with wind-heat invading lung syndrome,regulate the inflammatory state of the body,improve the disease symptoms,enhance the therapeutic effect,and has drug safety,which is worthy of promotion.

Suhuang Zhike CapsuleCommunity-acquired pneumoniaWind-heat invading lung syndromeSyndrome scoreInflammatory indicators

李维真、赵迪宏、罗建云、梁佩贞、李君、司徒淳羽

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529000 江门市人民医院

苏黄止咳胶囊 社区获得性肺炎 风热犯肺型 证候积分 炎症指标

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2023YL02026

2024

中国实用医药
中国康复医学会

中国实用医药

影响因子:0.797
ISSN:1673-7555
年,卷(期):2024.19(8)
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