Effect of Suhuang Zhike Capsule on syndrome score and inflammatory indicators of patients with community-acquired pneumonia with wind-heat invading lung syndrome
Objective To explore the effect of Suhuang Zhike Capsule on syndrome score and inflammatory indicators of patients with community-acquired pneumonia(CAP)with wind-heat invading lung syndrome.Methods 80 cases of CAP with wind-heat invading lung syndrome were randomly divided into an observation group and a control group,with 40 cases in each group.The control group was treated with Western medicine,and the observation group was treated with Suhuang Zhike Capsule on the basis of the control group.The syndrome score and inflammatory indicators before and after treatment,therapeutic effect and drug safety were compared between the two groups.Results After treatment,the scores of main symptoms,secondary symptoms and total score of the two groups were lower than those before treatment;the scores of main symptoms,secondary symptoms and total score of the observation group were(6.42±1.38),(3.08±0.84)and(9.38±1.48)points,which were lower than(8.48±2.81),(4.76±1.07)and(13.24±2.63)points of the control group;the differences were statistically significant(P<0.05).After treatment,the white blood cell count(WBC),neutrophils(NE),C-reactive protein(CRP)and procalcitonin(PCT)in both groups were improved compared with those before treatment;WBC,NE,CRP and PCT were(4.81±0.94)×109/L,(63.18±5.22)%,(7.52±1.11)mg/L and(0.17±0.05)ng/ml in the observation group,which were lower than(4.86±0.57)×109/L,(67.86±5.57)%,(9.47±1.85)mg/L and(0.34±0.06)ng/ml in the control group;the difference was statistically significant(P<0.05).The total effective rate of the observation group was 97.50%,which was higher than 82.50%of the control group,and the difference was statistically significant(P<0.05).No adverse reactions of allergy occurred in both groups during the treatment period.Conclusion Based on the theory of traditional Chinese medicine,Suhuang Zhike Capsule can act on the etiology and pathogenesis of CAP patients with wind-heat invading lung syndrome,regulate the inflammatory state of the body,improve the disease symptoms,enhance the therapeutic effect,and has drug safety,which is worthy of promotion.