Analysis of the predictive role of NIHSS score combined with CT angiography on the clinical prognosis of ultra-early acute ischemic stroke
Objective To evaluate the predictive value of National Institutes of Health Stroke scale(NIHSS)score combined with CT angiography(CTA)on the clinical prognosis of ultra-early acute ischemic stroke.Methods A total of 100 patients with ultra-early acute ischemic stroke were selected for this study,and the patients were divided into good prognosis group(NIHSS score≤4 points,52 cases)and poor prognosis group(NIHSS score>4 points,48 cases)according to NIHSS score after clinical treatment.The prognosis,NIHSS score and obstruction shown on CT angiography of patients with ultra-early acute stroke were compared between the two groups,and the single and multiple factors affecting the clinical prognosis of patients with ultra-early acute ischemic stroke were analyzed,and the receiver operating characteristic(ROC)curve of clinical prognosis of patients with ultra-early acute ischemic stroke was analyzed.Results The baseline NIHSS score,NIHSS score at discharge and neurological function recovery rate of patients with ultra-early acute ischemic stroke in the good prognosis group were(6.1±1.5)points,(2.4±0.5)points and(0.67±0.12),and those in the poor prognosis group were(11.8±2.3)points,(6.8±1.3)points and(0.46±0.19).Compared with the poor prognosis group,the good prognosis group had significantly lower baseline NIHSS scores and NIHSS scores at discharge,and significantly higher neurological function recovery rates(P<0.05).The results of univariate analysis showed that compared with the poor prognosis group,the baseline NIHSS score and the percentage of vascular obstruction shown on CT angiography were significantly lower in the good prognosis group(P<0.05).Multivariate regression analysis showed that high baseline NIHSS score and vascular obstruction shown on CT angiography were closely associated with early clinical prognosis of ultra-early acute ischemic stroke,and were independent risk factors for clinical prognosis of ultra-early acute ischemic stroke(P<0.05).As shown by ROC analysis,the sensitivity and specificity of NIHSS score combined with CT angiography model in predicting the clinical prognosis of ultra-early acute ischemic stroke were higher than that of baseline NIHSS score model and CT angiography model.Conclusion NIHSS score combined with CT angiography has outstanding predictive ability for the clinical prognosis of ultra-early acute ischemic stroke.
National Institutes of Health Stroke scale scoreCT angiographyUltra-early acute ischemic strokeBlood vessel occlusionClinical prognosis