The diagnostic value of PG-Ⅰ,PG-Ⅱ,G-17 combined with Helicobacter pylori IgG antibody test in gastric cancer
Objective To analyze the diagnostic value of pepsinogen Ⅰ(PG-Ⅰ),pepsinogen Ⅱ(PG-Ⅱ),gastrin-17(G-17)combined with Helicobacter pylori immunoglobulin G(IgG)antibody in gastric cancer.Methods A total of 76 patients with gastric cancer were selected as the gastric cancer group,and 114 healthy volunteers were selected as the control group.PGⅠ,PGⅡ,G-17,and Helicobacter pylori IgG antibody tests were performed on all study subjects included in this study.The the level of PGⅠ,PGⅡ,and G-17,and positive rate of Helicobacter pylori IgG antibody(type Ⅰ and type Ⅱ Helicobacter pylori)were analyzed and compared between the two groups.Results The gastric cancer group had significantly lower PGⅠ of(61.73±2.47)μg/L than(76.75±3.46)μg/L in the control group;the gastric cancer group had PG-Ⅱ of(16.57±0.46)μg/L and G-17 of(23.66±1.47)pmol/L,which were higher than(12.89±1.74)μg/L and(11.13±1.74)pmol/L in the control group;the difference was statistically significant(P<0.05).The positive rate of type Ⅰ Helicobacter pylori antibody(50.0％)in the gastric cancer group was higher than 29.8％in the control group,and the difference was statistically significant(P<0.05),but there was no significant difference in the positive rate of type Ⅱ Helicobacter pylori antibody between the two groups(P>0.05).Conclusion The combination of PGⅠ,PGⅡ,G-17 and Helicobacter pylori IgG antibody test for gastric cancer patients can help to improve the diagnostic accuracy,which can provide a scientific basis for the clinical diagnosis of gastric cancer.It is of great significance for the early prevention and treatment of gastric cancer,and is worthy of popularization and application.
Pepsinogen ⅠPepsinogen ⅡGastrin-17Helicobacter pylori IgG antibodyGastric cancer
万方数据
维普
