Effect analysis of transcatheter arterial chemoembolization on patients with primary liver cancer
Objective To explore the effect of transcatheter arterial chemoembolization on patients with primary liver cancer.Methods 88 cases of primary liver cancer were divided into an observation group and a control group using random number table method,with 44 cases in each group.The control group received hepatic artery infusion chemotherapy,and the observation group received transcatheter arterial chemoembolization.Patients in both groups were compared in terms of recurrence within 1 and 2 years after surgery,occurrence of postoperative complications,quality of life,liver function[alanine aminotrasferase(ALT),total bilirubin(TBIL),aspartate transaminase(AST)and hepatitis B virus deoxyribonucleic acid(HBV-DNA)]levels before and after treatment.Results The recurrence rate within 1 and 2 years after surgery in the observation group was slightly lower than that in the control group,but the difference was not statistically significant(P>0.05).Compared with 18.18%in the control group,the incidence of postoperative complications in the observation group was significantly lower at 4.55%,and the difference was significant(P<0.05).After treatment,the scores of social function,physical function,material life and psychological function increased in both groups;in the observation group,the social function score was(86.06±5.75)points,the physical function score was(82.75±4.09)points,the material life score was(81.64±5.43)points and the psychological function score was(80.70±5.88)points,which were higher than(72.42±6.91),(69.06±6.97),(68.76±6.75)and(68.86±6.48)points in the control group;the difference was significant(P<0.05).After treatment,the levels of ALT,TBIL,AST and HBV-DNA decreased in both groups;the observation group had ALT of(46.66±10.25)U/L,TBIL of(17.55±2.74)µmol/L,AST of(30.50±3.55)U/L,and HBV-DNA of(0.92±0.51)×103 copies/ml,which were lower than(57.68±10.44)U/L,(20.65±2.37)µmol/L,(36.72±3.11)U/L,and(2.82±0.71)×103 copies/ml in the control group;the difference was significant(P<0.05).Conclusion Transcatheter arterial chemoembolization has significant clinical effects in the treatment of primary liver cancer patients.Although the recurrence rate within 2 years after surgery is not significantly different from that of hepatic artery infusion chemotherapy,it can reduce the incidence of postoperative complications and is conducive to the improvement of patients'quality of life and liver function,so it is recommended to promote clinical application.
万方数据
维普
