Clinical curative effect of integrated traditional Chinese and Western medicine in treating cirrhosis with refractory ascites
Objective To explore the clinical efficacy of integrated traditional Chinese and Western medicine in treating cirrhosis with refractory ascites.Methods A total of 120 patients with cirrhosis with refractory ascites were divided into a control group and a study group according to the method of random number table,with 60 cases in each group.The control group was treated with conventional Western medicine,and the study group was treated with integrated traditional Chinese and Western medicine.The clinical efficacy,symptom subsidence time,adverse reactions,serum inflammatory factors,symptom score and quality of life were compared between the two groups.Results The total clinical effective rate of the study group was 98.33%,which was higher than the control group's 86.67%,and the difference was significant(P＜0.05).The subsidence time of abdominal distension,fatigue and abdominal pain in the study group were(4.12±0.76),(3.29±0.81)and(4.37±0.89)d,which were shorter than(5.30±0.93),(4.32±0.97)and(5.64±1.02)d in the control group,and the difference was significant(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).After treatment,the levels of C-reactive protein and interleukin-6 in both groups were significantly reduced compared with those before treatment;the study group had C-reactive protein of(5.89±1.06)mg/L and interleukin-6 of(21.83±2.17)pg/ml,which were lower than(7.02±1.27)mg/L and(25.49±2.76)pg/ml in the control group;the difference was significant(P＜0.05).After treatment,the scores of abdominal distension,fatigue and abdominal pain in both groups were significantly reduced compared with those before treatment;the study group had abdominal distension score of(1.17±0.39)points,fatigue score of(1.06±0.31)points and abdominal pain score of(1.16±0.40)points,which were lower than(1.58±0.43),(1.52±0.48)and(1.61±0.45)points in the control group;the differences were significant(P＜0.05).After treatment,the scores of physiology,psychology,environment and social relations in both groups were significantly higher than those before treatment;the study group had physiology score of(89.75±6.48)points,psychology score of(89.07±6.02)points,environment score of(90.14±6.15)points and social relation score of(89.96±6.27)points,which were all higher than(82.93±6.85),(82.40±6.13),(83.27±6.30)and(83.14±6.54)points in the control group;the difference was significant(P＜0.05).Conclusion In the treatment of cirrhosis with refractory ascites,the therapy of integrated traditional Chinese and Western medicine can accelerate the relief of symptoms and reduce the inflammatory reaction,and help improve the quality of life of patients,and the adverse reactions of integrated Chinese and western medicine have not increased.So is has good safety.
Hepatitis BHepatitis B cirrhosisRefractory ascitesIntegrated traditional Chinese and Western medicineChinese medicine
万方数据
维普
