首页|超声引导下PRP关节腔内精准注射辅助全内重建术在后交叉韧带损伤中的应用研究

超声引导下PRP关节腔内精准注射辅助全内重建术在后交叉韧带损伤中的应用研究

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目的 研究超声引导下富血小板血浆(PRP)关节腔内精准注射辅助全内重建术对后交叉韧带(PCL)损伤的临床治疗效果.方法 44 例住院手术治疗的PCL损伤患者,按随机数字表法分为对照组与试验组,每组 22 例.试验组实施超声引导下PRP关节腔内精准注射辅助全内重建术治疗,对照组实施全内重建术治疗,两组术后均进行功能锻炼.分析两组患者手术及随访情况,比较两组患者术后 6 个月移植物磁共振成像(MRI)评分及手术前后双膝后向松弛度差异值、国际膝关节文献委员会膝关节评估表(IKDC)评分、踝-后足美国足踝外科医师协会(AOFAS)评分.结果 两组患者手术均顺利完成,手术切口均愈合良好,正常出院后遵医嘱进行康复训练,并定期复查,所有患者均随访超过 1 年,随访过程中未发现自体供腱区相关并发症,未发现胫骨凹陷.术前及术后 3、6、12 个月,试验组患者患侧膝关节IKDC评分分别为(51.6±3.7)、(78.3±4.1)、(87.5±2.6)、(92.2±2.1)分,对照组分别为(50.5±4.7)、(74.8±4.2)、(82.9±4.0)、(90.2±3.1)分.术后 3、6、12 个月,两组患者患侧膝关节IKDC评分均较术前显著改善,同时术后 6、12 个月较术后 3 个月显著改善,术后 12 个月较术后 6 个月显著改善,差异均有统计学意义(P<0.05).试验组术后 3、6、12 个月患侧膝关节IKDC评分均显著优于对照组,差异均有统计学意义(P<0.05).术前及术后 3、6、12 个月,试验组患者患侧踝-后足AOFAS评分分别为(98.7±1.0)、(98.4±0.8)、(98.5±0.9)、(98.6±0.8)分,对照组分别为(98.2±0.9)、(98.0±0.8)、(98.3±0.9)、(98.4±1.0)分.术后第 3、6、12 个月,两组患者患侧踝-后足AOFAS评分与术前比较均无显著性差异(P>0.05);两组患者术前及术后 3、6、12 个月患侧踝-后足AOFAS评分组间比较无统计学差异(P>0.05).术后 6 个月复查膝关节MRI提示两组患者的重建韧带均走行良好,腱骨愈合情况满意.试验组术后 6 个月移植物MRI评分显著优于对照组,差异有统计学意义(P<0.05).术前,试验组双膝后向松弛度差异值为(13.6±1.4)mm,对照组双膝后向松弛度差异值为(13.9±1.5)mm;术后12 个月,试验组双膝后向松弛度差异值为 2~7 mm,平均(4.0±1.4)mm;对照组双膝后向松弛度差异值为2~6 mm,平均(3.5±1.2)mm.术后 12 个月,两组双膝后向松弛度差异值均较术前有显著改善,差异有统计学意义(P<0.05);术前及术后 12 个月,两组双膝后向松弛度差异值组间比较无统计学差异(P>0.05).结论 超声引导下PRP关节腔内精准注射辅助全内重建术能够加速PCL损伤患者膝关节功能恢复,有效促进移植物重塑和腱-骨愈合,临床疗效满意.
Study on application of ultrasound-guided intraarticular PRP precision injection assisted all-inside reconstruction for posterior cruciate ligament injury
Objective To study the clinical effect of ultrasound-guided intraarticular platelet rich plasma(PRP)precision injection assisted all-inside reconstruction for posterior cruciate ligament(PCL)injury.Methods 44 patients with PCL injuries who were hospitalized for surgical treatment were divided into a control group and an experimental group according to the random number table method,with 22 cases in each group.The experimental group underwent ultrasound-guided intraarticular PRP precision injection assisted all-inside reconstruction,while the control group underwent all-inside reconstruction surgery.Both groups underwent functional exercise after surgery.The surgery and follow-up conditions of the two groups were analyzed,and the magnetic resonance imaging(MRI)scores of the grafts at 6 months postoperatively and the difference of the posterior laxity of both knees preoperatively and postoperatively,the International Knee Documentation Committee Knee Evaluation(IKDC)scores,and the American Orthopedic Foot and Ankle Society(AOFAS)ankle hindfoot score were compared between the two groups.Results All patients in the two groups successfully completed the operation,and the surgical incisions healed well.After normal discharge,rehabilitation training was carried out according to the doctor's advice,and regular review was conducted.All patients were followed up for more than 1 year,and no complications related to the autodonor tendon area were found during the follow-up.Preoperatively and at 3,6,and 12 months postoperatively,the IKDC scores of the affected knee joints of the patients in the experimental group were(51.6±3.7),(78.3±4.1),(87.5±2.6),and(92.2±2.1)points,and those of the control group were(50.5±4.7),(74.8±4.2),(82.9±4.0),and(90.2±3.1)points.At 3,6,and 12 months postoperatively,the IKDC scores of the affected knee joints of patients in both groups were significantly improved compared with those preoperatively;while the improvement at 6 and 12 months postoperatively were more significant compared with that at 3 months postoperatively,and the improvement at 12 months postoperatively were more significant compared with that at 6 months postoperatively;the difference was statistically significant(P<0.05).The IKDC scores of the affected knee joints of the experimental group were significantly better than those of the control group at 3,6,and 12 months postoperatively,and the difference was statistically significant(P<0.05).Preoperatively and at 3,6,and 12 months postoperatively,the AOFAS ankle hindfoot scores of the patients in the experimental group were(98.7±1.0),(98.4±0.8),(98.5±0.9),(98.6±0.8)points,and those in the control group were(98.2±0.9),(98.0±0.8),(98.3±0.9),(98.4±1.0),and(98.4±1.0)points.The AOFAS ankle-hindfoot scores of the patients in both groups at 3,6,and 12 months postoperatively were not statistically significant from that preoperatively(P>0.05).There was also no statistically significant difference in AOFAS ankle-hindfoot scores preoperatively and at 3,6,and 12 months postoperatively between the groups(P>0.05).At 6 months postoperatively,a follow-up MRI of the knee joint showed that the reconstructed ligaments in both groups of patients were in good condition,and the tendon bone healing was satisfactory.The MRI scores of the grafts in the experimental group were significantly better than those in the control group at 6 months postoperatively,and the difference was statistically significant(P<0.05).Preoperatively,the difference of the posterior laxity of both knees were(13.6±1.4)mm in the experimental group and(13.9±1.5)mm in the control group;at 12 months postoperatively,the difference of the posterior laxity of both knees ranged from 2 to 7 mm in the experimental group,with an average of(4.0±1.4)mm;the difference of the posterior laxity of both knees ranged from 2 to 6 mm in the control group,with an average of(3.5±1.2)mm.At 12 months postoperatively,the difference of the posterior laxity of both knees in both groups was significantly improved compared with that preoperatively,the difference was statistically significant(P<0.05),but there was no statistical difference in difference of the posterior laxity of both knees between the two groups preoperatively and at 12 months postoperatively(P>0.05).Conclusion Ultrasound-guided intraarticular PRP precision injection assisted all-inside reconstruction can accelerate the functional recovery of knee joint in patients with PCL injury,effectively promote graft remodeling and tendine-bone healing,and the clinical efficacy is satisfactory.

Ultrasound-quidedPlatelet rich plasmaAll-inside reconstructionPosterior cruciate ligament injuryKnee function

杨庆磊、喻红英、刘慧敏、黄耀斌、朱文刚、张德

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512000 广东省韶关市粤北人民医院关节骨病科

512000 广东省韶关市粤北人民医院药学部

512000 广东省韶关市粤北人民医院超声影像科

超声引导 富血小板血浆 全内重建术 后交叉韧带 膝关节功能

广东省韶关市卫生健康科研项目

Y22038

2024

中国实用医药
中国康复医学会

中国实用医药

影响因子:0.797
ISSN:1673-7555
年,卷(期):2024.19(10)
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