Correlation between hyperuricemia and blood lipids,blood glucose,blood pressure in a population undergoing health examination
Objective To analyze the correlation between hyperuricemia(HUA)and blood lipids,blood glucose,blood pressure in a population undergoing health examination.Methods 218 subjects undergoing health examination,of which 106 patients with hyperuricemia selected as the experimental group and 112 patients with normal uric acid selected as the control group.The body mass index(BMI),incidence of atherosclerosis(AS),smoking,drinking and waist circumference of the two groups were recorded.The serum indexes,including blood urea nitrogen(BUN),triglyceride(TG),total cholesterol(TC),fasting blood glucose(GLU),as well as diastolic blood pressure(DBP)and systolic blood pressure(SBP)were detected to analyze the risk factors of hyperuricemia in subjects undergoing health examination.Results The TC,GLU,BMI,DBP,SBP,incidence of AS,TG,alcohol consumption ratio and waist circumference of male and female subjects undergoing health examination in the two groups were compared respectively,and the difference was statistically significant(P＜0.05).BUN level and smoking proportion of male and female subjects undergoing health examination in the two groups were compared,and the difference was not statistically significant(P＞0.05).The incidence of AS in the experimental group was 19.8%,TC was(5.0±0.8)mmol/L,DBP was(84.0±7.1)mm Hg(1 mm Hg=0.133 kPa),alcohol consumption accounted for 30.2%,BMI was(26.8±4.21)kg/m2,TG was(2.0±0.3)mmol/L,GLU was(5.7±0.76)mmol/L,waist circumference was(85.6±10.5)cm,and SBP was(130.4±3.6)mm Hg,and those in the control group were 3.6%,(4.7±0.7)mmol/L,(80.5±8.6)mm Hg,8.0%,(24.69±3.7)kg/m2,(1.56±0.3)mmol/L,(5.20±0.5)mmol/L,(62.51±10.2)cm,and(127.88±3.3)mm Hg;the difference was statistically significant(P＜0.05).There was no significant difference in smoking status and BUN level between the two groups(P＞0.05).Multivariate Logistic regression analysis showed that the incidence of AS,TC,TG,BMI,GLU and waist circumference were independent influencing factors for the occurrence of hyperuricemia(P＜0.05).Conclusion The increase of uric acid level is correlated with the changes of blood lipid,blood glucose,BMI,waist circumference.The increase of uric acid level is an important risk factor for the occurrence and development of AS.
万方数据
维普
