Summary of clinical experience in treating chronic renal failure with Kangshen recipe
Objective To explore the clinical efficacy of Kangshen recipe in treating chronic renal failure,and summarize its clinical experience.Methods 67 patients with chronic renal failure were divided into a control group(35 cases)and an observation group(32 cases)by odd and even number method.The control group received conventional western medicine treatment,and the observation group was treated with Kangshen recipe on the basis of the control group.Both groups were compared in termsof serum creatinine(Scr),creatinine clearance rate(Ccr),blood urea nitrogen(BUN),serum transforming growth factor-β1(TGF-β1),hemoglobin(Hb),urinary protein,serum albumin(ALB)and traditional Chinese medicine syndrome score before and after treatment,efficacy,and safety.Results After treatment,the observation group had Scr of(110.0±5.2)μmol/L,BUN of(6.6±0.2)mmol/L,TGF-β1 of(2.0±0.1)ng/ml and traditional Chinese medicine syndrome score of(4.83±1.91)points,which were lower than(138.0±7.2)μmol/L,(8.7±0.3)mmol/L,(3.1±0.1)ng/ml and(8.77±1.85)points in the control group;the observation group had higher Ccr of(71.0±0.8)ml/min than(55.4±0.7)ml/min in the control group(P＜0.05).After treatment,the total effective rate of 93.75%in the observation group was higher than 71.43%in the control group(P＜0.05).After treatment,there were no significant differences in Hb,urinary protein and ALB between the two groups(P＞0.05).No adverse reactions occurred during treatment in both groups.Conclusion Kangshen recipe is an empirical prescription based on"strengthening the kidney and the spleen",which is effective for chronic renal failure with spleen-kidney qi deficiency.
Kangshen recipeChronic renal failureStrengthening the kidney and the spleenSerum creatinineBlood urea nitrogenCreatinine clearance rate
万方数据
维普
