Analysis of therapeutic effect of Jinshuibao on chronic nephritis
Objective To analyze the therapeutic effect of Jinshuibao on chronic nephritis.Methods 84 cases of chronic nephritis were divided into a reference group and a research group using random number table method,with 42 patients in each group.The reference group was treated with valsartan,and the research group was treated with with Jinshuibao on the basis of the reference group.Comparison was made on renal function indicators[serum creatinine(Scr),blood urea nitrogen(BUN)],24-h urinary protein,levels of inflammatory factors[tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),hypersensitive C-reactive protein(hs-CRP)]and clinical efficacy between the two groups.Results After 3 months of treatment,the 24-h urinary protein,Scr and BUN of the research group were(1.12±0.51)g/24 h,(92.13±10.90)μmol/L and(5.13±1.09)mmol/L,which were lower than(1.51±0.76)g/24 h,(101.54±11.72)μmol/L and(5.94±1.17)mmol/L in the reference group,and there were statistical differences between groups(P<0.05).After 3 months of treatment,the levels of TNF-α,IL-6 and hs-CRP in the research group were(1.02±0.29)ng/ml,(116.13±25.34)ng/L and(7.08±1.05)mg/L,which were all lower than(1.44±0.31)ng/ml,(149.12±26.59)ng/L and(10.13±1.54)mg/L in the reference group,and there were statistical differences between groups(P<0.05).The total effective rate of the research group was 88.10%,which was higher than the reference group's 66.67%,and there was statistical difference between groups(P<0.05).Conclusion Jinshuibao has a significant therapeutic effect on chronic nephritis,which can improve the curative effect while both improving the yuan and consolidating the foundation.
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