首页|甲状腺微小乳头状癌中央区淋巴结转移影响因素分析及清扫意义

甲状腺微小乳头状癌中央区淋巴结转移影响因素分析及清扫意义

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目的 分析影响甲状腺微小乳头状癌中央区淋巴结转移的因素及清扫意义.方法 回顾性分析收治的 597 例甲状腺微小乳头状癌患者的临床资料,统计患者的性别、年龄、肿瘤直径、是否存在多发病灶、是否存在包膜侵犯、是否存在桥本甲状腺炎和中心淋巴结转移等情况.分析甲状腺微小乳头状癌中央区淋巴结转移的影响因素.结果 597 例患者均行病侧中央区淋巴结清扫术,转移161 例,占比 26.97%;无转移 436 例,占比 73.03%.年龄≤45 岁 236 例,占比 39.53%;>45 岁 361 例,占比 60.47%.肿瘤直径≤0.5 cm 322 例,占比 53.94%;>0.5 cm 275 例,占比 46.06%.单因素分析显示:转移患者的年龄≤45 岁占比 57.14%、男性占比 22.36%、肿瘤直径>0.5 cm占比 62.73%、有包膜侵犯占比 56.52%、多灶性占比 38.51%均高于无转移患者的 33.03%、13.76%、39.91%、42.89%、22.48%,差异具有统计学意义(P<0.05);无转移和转移患者的有无桥本甲状腺炎情况比较,差异无统计学意义(P>0.05).多因素Logistic回归分析结果显示:男性、年龄≤45 岁、肿瘤直径>0.5 cm、多灶性是甲状腺微小乳头状癌中央区淋巴结转移的独立危险因素(P<0.05).结论 是否合并桥本甲状腺炎与中央区淋巴结转移无关,男性、年龄≤45 岁、肿瘤直径>0.5 cm、多灶性是甲状腺微小乳头状癌发生中央区淋巴结转移的独立危险因素.
Analysis of factors affecting central lymph node metastasis in thyroid micropapillary carcinoma and the significance of clearance
Objective To analyze the factors affecting central lymph node metastasis in thyroid micropapillary carcinoma and the significance of clearance.Methods The clinical data of 597 cases of thyroid micropapillary carcinoma were retrospectively analyzed,and the gender,age,tumor diameter,whether it was multifocal,whether it invaded the capsule,and whether it was complicated with Hashimoto's thyroiditis and central lymph node metastasis were counted.The factors affecting central lymph node metastasis in thyroid micropapillary carcinoma was analyzed.Results All 597 patients underwent centralized lymph node dissection on the diseased side,including 161 cases with metastasis,accounting for 26.97%,and 436 cases without metastasis,accounting for 73.03%.Among them,236 cases were≤45 years of age,accounting for 39.53%;361 cases were>45 years of age,accounting for 60.47%.The tumor diameter was≤0.5 cm in 322 cases,accounting for 53.94%;>0.5 cm in 275 cases,accounting for 46.06%.Univariate analysis showed that 57.14%of metastatic patients were≤45 years of age,22.36%were male,62.73%had a tumor diameter>0.5 cm,56.52%had capsule invasion,and 38.51%were multifocal,which were higher than 33.03%,13.76%,39.91%,42.89%,and 22.48%in patients without metastasis,and the difference was statistically significant(P<0.05).There was no significant difference in Hashimoto thyroiditis between patients without metastasis and those with metastasis(P>0.05).Multivariate Logistic regression analysis showed that male,≤45 years of age,tumor diameter>0.5 cm,and multifocal were independent risk factors for central lymph node metastasis in papillary thyroid microcarcinoma(P<0.05).Conclusion There is no correlation between Hashimoto's thyroiditis and central lymph node metastasis.Male,≤45 years of age,tumor diameter>0.5 cm,multifocal,and capsule invasion are independent risk factors for central lymph node metastasis in thyroid micropapillary carcinoma.

Thyroid micropapillary carcinomaCentral lymph node metastasisMultifactorSignificance of clearance

刘经全

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024000 赤峰市医院

甲状腺微小乳头状癌 中央区淋巴结转移 多因素 清扫意义

赤峰市自然科学科研基金项目

SZR2023081

2024

10.14163/j.cnki.11-5547/r.2024.12.005

中国实用医药
中国康复医学会

中国实用医药

影响因子：0.797
ISSN：1673-7555
年,卷(期)：2024.19(12)