首页|烯丙雌醇与黄体酮注射液治疗先兆流产的临床疗效分析

烯丙雌醇与黄体酮注射液治疗先兆流产的临床疗效分析

扫码查看
目的 分析烯丙雌醇与黄体酮注射液治疗先兆流产的临床疗效.方法 40 例先兆流产患者,运用随机数字表法分为对照组和观察组,每组 20 例.对照组患者使用黄体酮注射液肌内注射,观察组患者使用烯丙雌醇口服.比较两组患者雌二醇、孕酮、人绒毛膜促性腺激素、炎性因子(降钙素原、白细胞介素-6)、临床疗效.结果 治疗后,观察组患者的雌二醇(967.19±96.54)pg/ml、孕酮(41.13±4.37)mmol/L、人绒毛膜促性腺激素(99860.24±946.52)mIU/ml与对照组的(768.42±54.64)pg/ml、(33.24±3.28)mmol/L、(64178.07±626.23)mIU/ml比较,居更高水平(P<0.05).治疗后,观察组患者的降钙素原(58.78±6.01)ng/L、白细胞介素-6(91.21±7.46)pg/ml与对照组的(93.57±9.13)ng/L、(152.42±10.58)pg/ml比较,居更低水平(P<0.05).观察组治疗总有效率95.00%与对照组的60.00%比较,居更高水平(P<0.05).结论 对于先兆流产患者而言,应用烯丙雌醇能够带来更高的保胎成功率,同时有效调节患者体内激素水平,降低炎性因子,具有较高的推广价值.
Analysis of the clinical efficacy of allylestrenol and progesterone injection in the treatment of threatened miscarriage
Objective To analyze the clinical efficacy of allylestrenol and progesterone injection in the treatment of threatened miscarriage.Methods 40 patients with threatened miscarriage were divided into a control group and an observation group by random number table method,with 20 cases in each group.The control group received intramuscular injection of progesterone injection,and the observation group received oral administration of allylestrenol.The estradiol,progesterone,human chorionic gonadotropin,inflammatory factors(procalcitonin,interleukin-6)and clinical efficacy were compared between the two groups.Results After treatment,the observation group had estradiol of(967.19±96.54)pg/ml,progesterone of(41.13±4.37)mmol/L,and human chorionic gonadotropin of(768.42±54.64)mIU/ml,which were higher than(99860.24±946.52)pg/ml,(33.24±3.28)mmol/L and(64178.07±626.23)mIU/ml in the control group(P<0.05).After treatment,the observation group had procalcitonin of(58.78±6.01)ng/L and interleukin-6 of(91.21±7.46)pg/ml,which were lower than(93.57±9.13)ng/L and(152.42±10.58)pg/ml in the control group(P<0.05).The total effective rate of the observation group was 95.00%,which was higher than 60.00%of the control group(P<0.05).Conclusion For patients with threatened miscarriage,the use of allylestrenol can bring a higher success rate in protecting the fetus,while effectively regulating the patient's hormone levels and reducing inflammatory factors,which has high promotion value.

AllylestrenolProgesterone injectionThreatened miscarriageClinical efficacy

赵丽云

展开 >

272200 金乡县人民医院

烯丙雌醇 黄体酮注射液 先兆流产 临床疗效

2024

中国实用医药
中国康复医学会

中国实用医药

影响因子:0.797
ISSN:1673-7555
年,卷(期):2024.19(12)