首页|探讨小剂量罗哌卡因联合舒芬太尼连续硬膜外麻醉对无痛分娩产妇镇痛效应及母婴结局的影响

探讨小剂量罗哌卡因联合舒芬太尼连续硬膜外麻醉对无痛分娩产妇镇痛效应及母婴结局的影响

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目的 探析应用小剂量罗哌卡因联合舒芬太尼连续硬膜外麻醉对无痛分娩产妇镇痛效应及母婴结局的影响.方法 纳入产科产检并拟用无痛分娩的 100 例产妇为分析对象,对产妇编序后采用随机数字表格方法分组,分设为对照组(罗哌卡因连续硬膜外麻醉)、观察组(小剂量罗哌卡因联合舒芬太尼连续硬膜外麻醉),各 50 例.比较两组产妇的麻醉镇痛效果(镇痛起效时间、完全阻滞时间、镇痛持续时间),产程(第一产程、第二产程、第三产程及总产程),不同时间段(镇痛前、镇痛后15 min、镇痛后 30 min、宫口开全时)疼痛评分,母婴结局.结果 观察组产妇的镇痛起效时间(4.56±1.68)min、完全阻滞时间(12.35±2.42)min显著短于对照组的(15.14±1.87)、(23.41±2.13)min,镇痛持续时间(5.38±0.57)h长于对照组的(2.66±0.33)h,有统计学意义(P<0.05).观察组产妇的第一产程(376.22±61.23)min及总产程(427.71±82.21)min显著短于对照组的(432.42±88.21)、(484.77±112.42)min,有统计学意义(P<0.05),两组第二产程及第三产程比较无统计学意义(P>0.05).观察组产妇镇痛后 15 min、镇痛后 30 min、宫口开全时疼痛评分分别为(1.78±0.34)、(1.23±0.24)、(1.54±0.28)分,显著低于对照组的(2.12±0.41)、(1.87±0.27)、(3.23±1.16)分,有统计学意义(P<0.05).两组新生儿出生后 10 min的Apgar评分及产妇恶心呕吐、头痛、尿潴留发生率比较无统计学意义(P>0.05).结论 产妇无痛分娩时应用小剂量罗哌卡因联合舒芬太尼连续硬膜外麻醉方式的镇痛效果显著,不会增加母婴结局不良风险.
Influence of low-dose ropivacaine combined with sufentanil continuous epidural anesthesia on the analgesic effect of parturients undergoing painless delivery and maternal and infant outcomes
Objective To explore the influence of low-dose ropivacaine combined with sufentanil continuous epidural anesthesia on the analgesic effect of parturients undergoing painless delivery and maternal and infant outcomes.Methods A total of 100 parturients who were included in obstetric examination and planned to have painless delivery were divided into a control group(ropivacaine continuous epidural anesthesia)and an observation group(low-dose ropivacaine combined with sufentanil continuous epidural anesthesia)according to random number table method after being sequenced,with 50 cases in each group.Comparison was made on anesthetic and analgesic effect(onset time of anesthesia,complete block time,analgesic duration),stage of labor(first stage,second stage,third stage and total stage of labor),pain scores at different time periods(before analgesia,15 min after analgesia,30 min after analgesia,when the cervix was fully dilated)and maternal and infant outcomes between the two groups.Results The observation group had onset time of analgesia of(4.56±1.68)min and complete block time of(12.35±2.42)min,which were significantly shorter than(15.14±1.87)and(23.41±2.13)min in the control group;the observation group had longer analgesic duration of(5.38±0.57)h than(2.66±0.33)h in the control group;there was statistical significance(P<0.05).The observation group had duration of the first stage of labor of(376.22±61.23)min and the total duration of labor of(427.71±82.21)min,which were significantly shorter than(432.42±88.21)and(484.77±112.42)min in the control group,and there was statistical significance(P<0.05).There was no statistical significance in the duration of the second and third stages of labor between the two groups(P>0.05).In the observation group,the pain scores 15 min after analgesia,30 min after analgesia and when the cervix was fully dilated were(1.78±0.34),(1.23±0.24)and(1.54±0.28)points,which were significantly lower than(2.12±0.41),(1.87±0.27)and(3.23±1.16)points in the control group.There was statistical significance(P<0.05).There was no significant difference in Apgar score 10 min after birth and the incidence of nausea,vomiting,headache and urinary retention between the two groups(P>0.05).Conclusion The analgesic effect of low-dose ropivacaine combined with sufentanil continuous epidural anesthesia in painless delivery is significant,and it will not increase the adverse risk of maternal and infant outcomes.

Painless deliveryRopivacaineSufentanilEpidural anesthesiaAnalgesic effectMaternal and infant outcomes

刘欣、曹桂林

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255000 淄博市妇幼保健院手术麻醉科

无痛分娩 罗哌卡因 舒芬太尼 硬膜外麻醉 镇痛效应 母婴结局

2024

中国实用医药
中国康复医学会

中国实用医药

影响因子:0.797
ISSN:1673-7555
年,卷(期):2024.19(12)