Clinical study of"Chaihu Qingshang Decoction"based on inflammatory network in treating vestibular neuritis
Objective To explore the clinical efficacy of"Chaihu Qingshang Decoction"based on inflammatory network in treating vestibular neuritis.Methods 60 patients with vestibular neuritis were randomly divided into a control group(30 cases)and an observation group(30 cases).Patients in the control group received conventional medical treatment,and patients in the observation group were treated with"Chaihu Qingshang Decoction"on the basis of conventional medical treatment.Patients in both groups were compared in terms of neutrophil-to-lymphocyte ratio(NLR),platelet-to-lymphocyte ratio(PLR),C-reactive protein(CRP),vertigo disability score,double temperature test and head impulsive test before and after treatment.Results The levels of NLR,PLR and CRP in both groups after 14 and 90 d of treatment were decreased compared with those before treatment,and the data comparison was statistically significant(P<0.05).After 14 and 90 d of treatment,the levels of NLR,PLR and CRP in the observation group were significantly reduced compared with those in the control group,the data comparison was statistically significant(P<0.05).Before treatment,the vertigo disability score in the control group was(23.44±7.17)points,and that in the observation group was(22.92±6.63)points.After treatment,the vertigo disability score in the control group was(16.53±6.25)points,and that in the observation group was(12.31±5.46)points.After treatment,the vertigo disability score in both groups was decreased compared with that before treatment,and the vertigo disability score in the observation group was significantly lower than that in the control.The data comparison was statistically significant(P<0.05).The canal paresis(CP)value of the observation group was(15.24±4.11)%after treatment,which was significantly lower than(21.23±4.55)%of the control group,and the data comparison was statistically significant(P<0.05).After treatment,the proportion of compensated eye movement in both groups was lower than that before treatment,and the proportions of regression gain≥0.90 and regression gain asymmetry ratio≤12%were higher than those before treatment.The data comparison was statistically significant(P<0.05).The proportion of compensated eye movement after treatment in the observation group was lower than that in the control group,and the proportions of regression gain≥0.90 and regression gain asymmetry ratio≤12%were higher than those in the control group,but the data comparison was statistically significant(P>0.05).Conclusion The treatment of"Chaihu Qingshang Decoction"in patients with vestibular neuritis can reduce the inflammatory response,improve the clinical symptoms of vertigo,tinnitus,nausea and vomiting,promote the recovery of vestibular function,the overall prognosis is good,and can reduce the incidence of chronic dizziness caused by vestibular neuritis,so it is worthy of clinical promotion and wide application.
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