Study on effect of different blood glucose levels on prognosis of patients with acute cerebral infarction
Objective To explore the effect of different blood glucose levels on prognosis of patients with acute cerebral infarction.Methods 60 patients with acute cerebral infarction were selected as subjects and divided into a control group and an observation group according to whether diabetes was combined or not,with 30 cases in each group,corresponding to non-diabetic patients with acute cerebral infarction and diabetic patients with acute cerebral infarction,respectively.After admission,the two groups of patients received corresponding routine symptomatic supportive treatment,and the efficacy,prognosis,neurological function and blood glucose fluctuation of the two groups were compared.Results The 24 h mean blood glucose,standard deviation of blood glucose,mean blood glucose fluctuation and maximum blood glucose fluctuation were(8.28±1.83),(2.09±0.41),(4.27±0.65)and(3.10±0.46)mmol/L in the observation group,which were higher than(5.76±1.09),(1.57±0.32),(3.23±0.36)and(2.19±0.34)mmol/L in the control group,and the difference between groups was significant(P<0.05).The difference in cerebral hemorrhage conversion rate between the two groups was not significant when compared between the groups(P>0.05).The excellent recanalization rate and excellent prognosis rate of the observation group were 33.33%and 30.00%,which were lower than 63.33%and 60.00%of the control group,and the difference between the groups was statistically significant in comparison(P<0.05).There was no significant difference in the score of National Institutes of Health Stroke Scale(NIHSS)before treatment between the two groups(P>0.05).After treatment,the NIHSS score of the two group was lower than that before treatment;the NIHSS score of the observation group was(10.78±2.14)points,which was higher than(8.10±1.57)points of the control group,and the difference was significant(P<0.05).The total effective rate of the observation group was 73.33%,which was lower than 96.67%of the control group,and the difference was significant(P<0.05).Conclusion Blood glucose fluctuation will have a certain adverse effect on the treatment and prognosis of patients with acute cerebral infarction,which should be paid attention to,and the blood glucose level should be actively controlled in the actual treatment.
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