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抗凝治疗前婴儿川崎病出现消化道出血1例

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为探究治疗前婴儿川崎病合并消化道出血的临床特征及治疗过程,本文特选取1例男性患儿临床资料进行分析,患儿发热2 d入院.最高体温39.5℃,日热峰4~5次.症状体征为反复发热、易激惹、精神差、结膜充血、红色斑疹、卡疤红、颈部可触及肿大淋巴结、口唇潮红、皲裂、杨梅舌、手足末端硬性红肿、肝大.发病第 5 天呕吐咖啡样物及出现柏油样大便,3~4 次/d,每次 10 ml左右.急性期采用丙种球蛋白、抗血小板、糖皮质激素、抗生素治疗,恢复期采用抗血小板治疗.临床转归,症状消失,实验室指标正常或接近正常,病情好转出院.随访未出现冠状动脉(冠脉)病变,消化道出血痊愈.
Gastrointestinal hemorrhage before anticoagulant therapy in infantile Kawasaki disease:a case report
In this paper,the clinical data of a male child is analyzed to investigate the clinical characteristics and treatment process of infantile Kawasaki disease combined with gastrointestinal bleeding.The child is admitted to the hospital with fever for 2 d.The highest temperature was 39.5℃,and the fever peaked 4-5 times a day.Symptoms and signs are recurrent fever,irritability,poor spirit,conjunctival congestion,red maculopapular rash,scarlet,neck palpable enlarged lymph nodes,flushed lips,chapped,poplar tongue,hard redness and swelling of the ends of the hands and feet,and hepatomegaly.On the 5th day of the disease,coffee-like material was vomited and tarry stools appeared,3-4 times/d,the amount was about 10 ml each time.The patient is treated with gamma globulin,antiplatelet,glucocorticoid,antibiotics in the acute stage,and antiplatelet therapy in the recovery stage.The patient has discharged from the hospital after clinical regression,disappearance of symptoms,and improvement of normal or near-normal laboratory indicators.No coronary artery lesions are found on follow-up,and gastrointestinal bleeding is cured.

Gastrointestinal bleedingKawasaki diseaseGamma globulinGlucocorticoidAntiplatelet therapy

赵春兰、袭学芹

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250014 山东省妇幼保健院呼吸科

消化道出血 川崎病 丙种球蛋白 糖皮质激素 抗血小板治疗

2024

中国实用医药
中国康复医学会

中国实用医药

影响因子:0.797
ISSN:1673-7555
年,卷(期):2024.19(13)