首页|补阳还五汤联合胞磷胆碱治疗气虚血瘀型脑梗死恢复期的临床疗效分析

补阳还五汤联合胞磷胆碱治疗气虚血瘀型脑梗死恢复期的临床疗效分析

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目的 分析补阳还五汤联合胞磷胆碱治疗气虚血瘀型脑梗死恢复期患者的临床疗效.方法 90 例气虚血瘀型脑梗死恢复期患者,随机分为A组与B组,每组 45 例.A组使用胞磷胆碱钠胶囊治疗,B组使用补阳还五汤+胞磷胆碱钠胶囊治疗.比较两组患者的临床疗效、不良反应发生情况及治疗前后功能评分[美国国立卫生研究院卒中量表(NIHSS)评分、生活质量量表(QOL)评分和Barthel指数].结果 B组患者治疗总有效率为 95.6%,高于A组的 66.7%,组间对比有统计学差异(P<0.05).A组患者不良反应发生率为 4.4%(2/45),与B组的 6.7%(3/45)对比无统计学差异(P>0.05).治疗后,两组患者NIHSS评分显著降低,QOL评分和Barthel指数明显升高,且B组NIHSS评分(5.6±2.7)分低于A组的(8.7±2.2)分,QOL评分(77.7±11.2)分、Barthel指数(59.5±10.2)分均高于A组的(57.5±10.0)、(39.7±7.9)分,组间对比有统计学差异(P<0.05).结论 补阳还五汤与胞磷胆碱联合治疗气虚血瘀型脑梗死恢复期效果良好,值得推广.
Analysis of clinical efficacy of Buyang Huanwu Tang combined with citicoline in the treatment of Qi deficiency and blood stasis type cerebral infarction
Objective To analyze the clinical efficacy of Buyang Huanwu Tang combined with citicoline in the treatment of Qi deficiency and blood stasis type cerebral infarction.Methods 90 patients with Qi deficiency and blood stasis type cerebral infarction were randomly divided into group A and group B,each with 45 cases.Group A was treated with citicoline sodium capsules,while group B was treated with Buyang Huanwu Tang+citicoline sodium capsules.Patients in both groups were compared in terms of clinical efficacy,occurrence of adverse reactions and functional scores[National Institutes of Health Stroke Scale(NIHSS)score,Quality of Life Scale(QOL)score and Barthel index]before and after treatment.Results The total effective rate of group B was 95.6%,which was higher than 66.7%of group A,and the difference between groups was statistically significant(P<0.05).The incidence of adverse reactions in group A was 4.4%(2/45),which had no significant difference compared with 6.7%(3/45)in group B(P>0.05).After treatment,NIHSS score decreased significantly,QOL score and Barthel index increased significantly in both groups;group B had lower NIHSS score of(5.6±2.7)points than(8.7±2.2)points in group A;group B had QOL score of(77.7±11.2)points and Barthel index of(59.5±10.2)points,which were higher than(57.5±10.0)and(39.7±7.9)points in group A;the difference between groups was statistically significant(P<0.05).Conclusion The combination of Buyang Huanwu Tang and citicoline has a good effect on the recovery period of Qi deficiency and blood stasis type cerebral infarction,and is worth promoting.

Qi deficiency and blood stasis type cerebral infarctionBuyang Huanwu TangAdverse reactionsCiticoline

徐晖、林燕、何渊、石一杰

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511399 广东省广州市增城区中医医院

气虚血瘀型脑梗死 补阳还五汤 不良反应 胞磷胆碱

2024

中国实用医药
中国康复医学会

中国实用医药

影响因子:0.797
ISSN:1673-7555
年,卷(期):2024.19(14)