首页|双侧星状神经节阻滞联合穴位注射治疗过敏性鼻炎的效果观察

双侧星状神经节阻滞联合穴位注射治疗过敏性鼻炎的效果观察

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目的 观察过敏性鼻炎患者实施双侧星状神经节阻滞(SGB)联合穴位注射治疗的效果.方法 600 例过敏性鼻炎患者,以随机性为分组原则分为对照组(300 例)、观察组(300 例).对照组实施双侧SGB治疗,观察组在对照组基础上实时穴位注射治疗.比较两组的治疗效果、不良事件发生情况、免疫指标[免疫球蛋白E(IgE)]与炎性因子[白细胞介素-4(IL-4)、白细胞介素-6(IL-6)、白细胞介素-10(IL-10)、白三烯B4(LTB4)]水平、临床症状积分.结果 观察组治疗总有效率 98.33%高于对照组的 78.33%(P<0.05).两组不良事件发生率比较差异较小(P>0.05).治疗后,观察组IgE(45.38±4.77)IU/ml、IL-4(18.82±1.20)pg/ml、IL-6(16.55±1.72)pg/ml、IL-10(13.55±1.08)pg/ml、LTB4(53.58±5.77)ng/L均低于对照组的(77.82±7.11)IU/ml、(25.77±2.55)pg/ml、(26.55±2.58)pg/ml、(19.91±1.25)pg/ml、(72.58±7.72)ng/L(P<0.05).治疗前,两组喷嚏、流涕、鼻塞、鼻痒积分比较差异较小(P>0.05);治疗后,观察组喷嚏、流涕、鼻塞、鼻痒积分分别为(0.53±0.10)、(0.48±0.20)、(0.45±0.10)、(0.40±0.05)分,均低于对照组的(0.98±0.12)、(0.81±0.13)、(0.88±0.20)、(0.89±0.12)分(P<0.05).结论 对过敏性鼻炎患者实施双侧SGB联合穴位注射治疗,疗效和安全性均较高.
Observation on the effect of bilateral stellate ganglion block combined with acupoint injection in the treatment of allergic rhinitis
Objective To observe the effect of bilateral stellate ganglion block(SGB)combined with acupoint injection in the treatment of allergic rhinitis.Methods 600 patients with allergic rhinitis were randomly divided into a control group(300 cases)and an observation group(300 cases).The control group received bilateral SGB treatment,and the observation group received real-time acupoint injection treatment on the basis of the control group.Both groups were compared in terms of therapeutic effect,occurrence of adverse events,levels of immune indicators[immunoglobulin E(IgE)]and inflammatory factors[interleukin-4(IL-4),interleukin-6(IL-6),interleukin-10(IL-10),leukotriene B4(LTB4)]and clinical symptom scores.Results The total effective rate of the observation group was 98.33%,which was higher than 78.33%of the control group(P<0.05).There was little difference in the incidence of adverse events between the two groups(P>0.05).After treatment,the observation group had IgE of(45.38±4.77)IU/ml,IL-4 of(18.82±1.20)pg/ml,IL-6 of(16.55±1.72)pg/ml,IL-10 of(13.55±1.08)pg/ml,and LTB4 of(53.58±5.77)ng/L,which were lower than(77.82±7.11)IU/ml,(25.77±2.55)pg/ml,(26.55±2.58)pg/ml,(19.91±1.25)pg/ml,and(72.58±7.72)ng/L of the control group(P<0.05).Before treatment,the difference in scores of sneezing,runny nose,stuffy nose and itchy nose between the two groups were relatively small(P>0.05).After treatment,the scores of sneezing,runny nose,stuffy nose and itchy nose in the observation group were(0.53±0.10),(0.48±0.20),(0.45±0.10)and(0.40±0.05)points,which were lower than(0.98±0.12),(0.81±0.13),(0.88±0.20)and(0.89±0.12)points in the control group(P<0.05).Conclusion Implementing bilateral SGB combined with acupoint injection therapy for patients with allergic rhinitis has high efficacy and safety.

Non-infectious allergic reactionsAllergic rhinitisStellate ganglion blockAcupoint injection

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253500 陵城区人民医院

非感染性变态反应 过敏性鼻炎 星状神经节阻滞 穴位注射

2024

中国实用医药
中国康复医学会

中国实用医药

影响因子:0.797
ISSN:1673-7555
年,卷(期):2024.19(14)