Comparison on the effects of low incision surgery and traditional thyroid surgery for patients with benign thyroid nodules and its impact on traumatic stress response
Objective To compare the application effect of low incision surgery and traditional thyroid surgery for patients with benign thyroid nodules and its impact on traumatic stress response.Methods 110 patients with benign thyroid nodules were observed.Collect the hospitalization numbers of enrolled patients and group them according to single or double numbers.Among them,55 single number patients were listed as the control group and 55 double number patients were listed as the observation group.The control group received traditional thyroid surgery,while the observation group received low incision surgery.Both groups were compared in terms of intraoperative bleeding volume,surgical time,incision length,intubation time,hospitalization days,pain scores at the end of surgery,6 h after surgery and 12 h after surgery traumatic stress response related indicators[epinephrine(E),ultrasensitive C-reactive protein(hs-CRP),interleukin-6(IL-6),and cortisol(COR)]at 1 h before surgery and 24 h after surgery,occurrence of postoperative complications,and clinical efficacy.Results The intraoperative bleeding volume of the observation group was(40.56±3.15)ml,which was less than(73.66±1.27)ml of the control group;the surgical time of the observation group was(40.66±1.19)min,the intubation time was(2.33±0.12)d,the hospitalization days was(4.55±0.13)d,and the incision length was(4.21±0.12)cm which were significantly shorter than(64.62±2.08)min,(3.98±0.17)d,(7.01±0.14)d,and(6.55±0.35)cm of the control group(P<0.05).The pain scores of the observation group were(1.49±0.12),(4.12±0.13)and(3.55±0.14)points at the end of surgery,6 h after surgery,and 12 h after surgery,which were significantly lower than(1.75±0.11),(4.66±0.17)and(4.21±0.19)points of the control group at the same time point(P<0.05).1 h before surgery,the levels of E,hs-CRP,IL-6 and COR were compared between the two groups,and there were no significant differences between the two groups(P>0.05).24 h after surgery,the levels of E,hs-CRP,IL-6 and COR in both groups were significantly higher than those in this group 1 h before surgery(P<0.05).24 h after surgery,the levels of E,hs-CRP,IL-6 and COR in the observation group were(180.33±1.15)ng/ml,(1.59±0.21)mg/L,(3.71±0.12)ng/L and(182.52±2.08)μg/L,which were significantly lower than(223.15±3.37)ng/ml,(5.62±0.31)mg/L,(5.99±0.17)ng/L and(285.36±6.17)μg/L in the control group at the same time point(P<0.05).The total incidence of postoperative complications in the observation group was 5.45%(3/55),which was significantly lower than 18.18%(10/55)in the control group(P<0.05).The total effective rate of the observation group was 96.36%,which was significantly higher than 80.00%in the control group(P<0.05).Conclusion The comprehensive effect of low incision surgery for the treatment of benign thyroid nodules is better,and the patient's traumatic stress response is less.
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