The effect of right heart failure on fluid responsiveness in septic shock
Objective To study the effect of right heart failure on fluid responsiveness in septic shock.Methods 16 patients with septic shock were divided into septic shock without right heart failure group(7 cases)and septic shock with right heart failure group(9 cases)according to the diagnostic criteria of right heart failure.The general data of the subjects were collected,and the central venous pressure(CVP)was measured and severe cardiac ultrasound was performed.Both groups were compared in terms of age,gender,Acute Physiology and Chronic Health Evaluation(APACHE Ⅱ)score,Sequential Organ Failure Assessment(SOFA)score,left ventricular ejection fraction(LVEF),right ventricular end-diastolic area(RVEDA),left ventricular end-diastolic area(LVEDA),RVEDA/LVEDA,pre-rehydration velocity time integral(VTI),post-rehydration VTI,and ∆VTI.Results There was no statistical difference in the comparison of age,gender,APACHE Ⅱ score,SOFA score,LVEF,LVEDA,pre-rehydration VTI,and post-rehydration VTI between the two groups(P>0.05).The RVEDA was(2.00±0.35)cm2 in septic shock without right heart failure group,which was smaller than(2.42±0.35)in septic shock with right heart failure group;the RVEDA/LVEDA was(0.47±0.03)in septic shock without right heart failure group,which was lower than(0.62±0.02)in septic shock with right heart failure group;the ∆VTI was(20.83±8.35)%in septic shock without right heart failure group,which was higher than(11.40±7.06)%in septic shock with right heart failure group;the difference was statistically significant(P<0.05).Conclusion Right heart failure has an effect on fluid responsiveness in septic shock.
Right heart failureSeptic shockFluid responsiveness