首页|术中冰冻切片对甲状腺乳头状癌的诊断准确性分析

术中冰冻切片对甲状腺乳头状癌的诊断准确性分析

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目的 探讨术中冰冻切片(FS)诊断甲状腺乳头状癌(PTC)的准确性和价值,并对提高诊断准确性的措施进行思考.方法 选择 40 例疑似PTC患者,均进行术中FS病理诊断、石蜡切片病理诊断、B超引导下的细针吸取细胞学(FNAC)检查.以石蜡切片诊断结果作为金标准,分析术中FS的诊断准确性、敏感性和特异性.结果 40 例患者经石蜡切片诊断后共有 39 例确诊为PTC,将其作为金标准;经术中FS诊断后共有 38 例确诊,其中仅有 1 例漏诊,FS诊断准确率为 97.50%(39/40),敏感性为94.74%(38/39),特异度为 100.00%(1/1).B超报告病灶为 3、4、5 类甲状腺结节;术中FS对 3、4、5 类甲状腺结节的诊断准确率分别为 100.00%、92.31%、100.00%.结论 术中FS在PTC的诊断中可以取得与石蜡切片相对一致的结果,而且术中FS所谓时间短,通常不超过 30 min,操作简单,更具实用性.
Analysis of accuracy of intraoperative frozen section in the diagnosis of papillary thyroid carcinoma
Objective To explore the accuracy and value of intraoperative frozen section(FS)in the diagnosis of papillary thyroid carcinoma(PTC),and considere the measures to improve the diagnostic accuracy.Methods A total of 40 suspected PTC patients were selected for intraoperative FS pathological diagnosis,paraffin section pathological diagnosis,and fine needle aspiration cytology(FNAC)guided by B-ultrasound.The diagnostic results of paraffin sections were used as the gold standard.The diagnostic accuracy,sensitivity and specificity of intraoperative FS were analyzed.Results A total of 39 of 40 patients were diagnosed with PTC after paraffin section diagnosis,which was used as the gold standard.A total of 38 cases were confirmed after diagnosis by FS,of which only 1 case was missed.The diagnostic accuracy,sensitivity and specificity of FS were 97.50%(39/40),94.74%(38/39)and 100.00%(1/1).B-ultrasound reported lesions as category 3,4,and 5 thyroid nodules;the diagnostic accuracy of intraoperative FS for category 3,4,and 5 thyroid nodules were 100.00%,92.31%,and 100.00%.Conclusion Intraoperative FS can achieve relatively consistent results with paraffin sections in the diagnosis of PTC,and the time required for intraoperative FS is short,usually not more than 30 min,simple and more practical.

Papillary thyroid carcinomaPathologic diagnosisParaffin sectionFrozen section

栗玉娇、孙骐、黄增通、戴伟平、齐彬

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524002 广东省农垦中心医院

510060 中山大学肿瘤防治中心

甲状腺乳头状癌 病理诊断 石蜡切片 术中冰冻切片

2024

中国实用医药
中国康复医学会

中国实用医药

影响因子:0.797
ISSN:1673-7555
年,卷(期):2024.19(15)
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