Analysis of accuracy of intraoperative frozen section in the diagnosis of papillary thyroid carcinoma
Objective To explore the accuracy and value of intraoperative frozen section(FS)in the diagnosis of papillary thyroid carcinoma(PTC),and considere the measures to improve the diagnostic accuracy.Methods A total of 40 suspected PTC patients were selected for intraoperative FS pathological diagnosis,paraffin section pathological diagnosis,and fine needle aspiration cytology(FNAC)guided by B-ultrasound.The diagnostic results of paraffin sections were used as the gold standard.The diagnostic accuracy,sensitivity and specificity of intraoperative FS were analyzed.Results A total of 39 of 40 patients were diagnosed with PTC after paraffin section diagnosis,which was used as the gold standard.A total of 38 cases were confirmed after diagnosis by FS,of which only 1 case was missed.The diagnostic accuracy,sensitivity and specificity of FS were 97.50%(39/40),94.74%(38/39)and 100.00%(1/1).B-ultrasound reported lesions as category 3,4,and 5 thyroid nodules;the diagnostic accuracy of intraoperative FS for category 3,4,and 5 thyroid nodules were 100.00%,92.31%,and 100.00%.Conclusion Intraoperative FS can achieve relatively consistent results with paraffin sections in the diagnosis of PTC,and the time required for intraoperative FS is short,usually not more than 30 min,simple and more practical.