Objective To analyze the clinical value of ultrasonic detection of yolk sac status and baseline thromboelastography in evaluating different pregnancy outcomes and anticoagulation outcomes.Methods A total of 215 pregnant women were collected,of which 87 normal pregnant women with early pregnancy were selected as group A,128 pregnant women with early symptoms of abortion such as vaginal bleeding and lower abdominal pain were divided into group B(threatened abortion with good pregnancy outcome,70 cases)and group C(threatened abortion with poor pregnancy outcome,58 cases)according to the different pregnancy outcomes.The patients were examined by transvaginal ultrasound,and data such as the diameter of the yolk sac,the size of the gestational sac,the length of the fetal bud,and the presence or absence of primitive heart tube pulses were recorded.Thromboelastographic coagulation analysis was performed on pregnant women,and the reaction time(R)value,clotting time(K)value,Angel angle,maximum amplitude value,and clot index(CI)value were recorded.Comparison of ultrasound testing of yolk sacs(display rate of yolk sac,diameter of yolk sac),baseline data of thromboelastography among the three groups,and changes in thromboelastography indicators before and after the treatment of pregnant women with hypercoagulation at 8-12 and 12-16 weeks'gestation in group C.Results The display rate of yolk sac was 89.66%in group A,87.14%in group B,which was higher than 55.17%in group C,and the difference was statistically significant(P<0.05).There was significant difference in the display rate of yolk sac among the three groups(P<0.05).The yolk sac diameter of group A and group C was higher than that of group B at 7-8,8-9,9-10,10-11 and 11-12 weeks'gestation,and group A was smaller than group C.The difference was statistically significant(P<0.05).There were significant differences in yolk sac diameter among the three groups at 7-8,8-9,9-10,10-11 and 11-12 weeks'gestation(P<0.05).The R value,K value,Angel Angle,MA value and CI value of the three groups were compared,and the difference was statistically significant(P<0.05).The R and K values of pregnant women in group C were lower than those in group A and group B,while the Angel angle,MA and CI values of pregnant women in group C were higher than those in group A and group B.The difference was statistically significant(P<0.05).There were 25 pregnant women in group C who developed hypercoagulation at 8-12 weeks'gestation,and 28 pregnant women who developed hypercoagulation at 12-16 weeks'gestation.The R value,K value,Angel angle,MA value,and CI value of pregnant women with hypercoagulation at 8-12 weeks'gestation in group C were(7.31±0.45)min,(1.96±0.31)min,(75.78±7.21)°,(62.21±7.11)mm,and(2.78±0.51)after treatment,which were superior to(5.79±0.51)min,(0.99±0.33)min,(86.29±6.21)°,(71.78±7.29)mm,and(5.51±1.21)before treatment,and the difference was statistically significant(P<0.05).The R value,K value,Angel angle,MA value,and CI value of pregnant women with hypercoagulation at 12-16 weeks'gestation in group C were(7.01±0.44)min,(1.92±0.34)min,(75.12±7.11)°,(61.21±7.49)mm,(2.32±0.31)after treatment,which were better than(5.51±0.41)min,(0.91±0.31)min,(88.29±6.48)°,(73.78±7.21)mm,and(5.62±1.01)before treatment,and the difference was statistically significant(P<0.05).Conclusion The diameter of the yolk sac detected by ultrasound is related to the pregnancy outcome.If it is too large or too small,it will lead to miscarriage.Baseline thromboelastography indicators can effectively reflect the probability of miscarriage.Patients with hypercoagulation have improved indicators after anticoagulation treatment.Therefore,baseline thromboelastography indicators can be used to evaluate the effectiveness of anticoagulation therapy and guide clinical anticoagulation treatment.
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