Study on clinical effect of transabdominal preperitoneal hernia repair in the treatment of inguinal hernia
Objective To analyze the clinical effect of transabdominal preperitoneal hernia repair(TAPP)in the treatment of inguinal hernia.Methods 98 cases of inguinal hernia patients were selected and divided into a control group(49 cases)and an observation group(49 cases)according to the order of admission.The control group was treated with traditional hernia repair,while the observation group was treated with TAPP.The indexes of gastrointestinal function,serum inflammatory factors,stress hormone indexes,pain factors and quality of life before and after surgery were compared between the two groups.Results In the observation group,the recovery time of bowel sound was(14.31±3.20)h,the first anal exhaust time was(18.73±1.35)h and the first defecation time was(25.75±2.27)h,which were shorter than(17.09±5.78),(21.98±2.39)and(39.41±3.60)h in the control group(t=2.945,8.288,22.467;P<0.05).2 d after surgery,the levels of interleukin-6,interleukin-8,C-reactive protein and tumor necrosis factor-α in the observation group were(15.21±2.15)ng/L,(43.53±6.12)ng/L,(7.78±1.20)mg/L and(26.67±5.11)ng/L,which were lower than(18.28±3.62)ng/L,(65.21±7.76)ng/L,(10.56±1.75)mg/L and(32.25±7.63)ng/L in the control group(t=5.104,15.356,9.171,4.523;P<0.05).2 d after surgery,the levels of cortisol,norepinephrine,aldosterone and angiotensin-Ⅱ in the observation group were(259.72±13.10)nmol/L,(92.21±11.82)μg/L,(15.45±2.51)ng/dl and(13.11±1.28)ng/L,which were lower than(412.89±15.01)nmol/L,(107.16±15.90)μg/L,(19.91±3.20)ng/dl and(20.73±2.40)ng/L in the control group(t=53.818,5.282,7.677,19.610;P<0.05).2 d after surgery,the levels of calcitonin gene-related peptide,substance P and prostaglandin E2 in the observation group were(261.74±35.15)ng/ml,(115.12±12.82)pmol/L and(16.83±3.15)ng/L,which were lower than(318.98±39.02)ng/ml,(169.41±20.86)pmol/L and(23.98±3.02)ng/L in the control group(t=7.629,15.521,11.469;P<0.05).1 month after surgery,the scores of physical function,role-physical,bodily pain,general health status,energy,social function,role-emotional and mental health of the observation group were higher than those of the control group(t=22.881,10.364,8.796,17.771,13.197,14.397,17.285,15.562;P<0.05).Conclusion TAPP has a good effect in patients with inguinal hernia,which can reduce the levels of stress hormone and pain factors,and help the patients to return to normal life as soon as possible.
Transabdominal preperitoneal hernia repairInguinal herniaStress hormone indexPain factorQuality of life
万方数据
维普
