首页|尿路感染合并血流感染患者病原菌检出情况及危险因素分析

尿路感染合并血流感染患者病原菌检出情况及危险因素分析

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目的 分析尿路感染合并血流感染患者尿液、血培养标本中病原菌分布特点,并探讨合并血流感染的危险因素,指导临床制定针对性防治措施.方法 回顾性分析 160 例尿路感染患者的临床资料.分析尿路感染合并血流感染的病原学特点;比较合并血流感染组与非血流感染组的一般资料、尿路感染相关资料,并分析尿路感染合并血流感染的危险因素.结果 160 例尿路感染患者中合并血流感染 28 例,占 17.50%.28 例尿路感染合并血流感染患者血培养分离出 35 株病原菌,合并血流感染组患者年龄≥80 岁、绝对卧床、有糖尿病病史、原发病为泌尿系统疾病、导尿管留置时间≥7 d、有多重耐药菌感染史、有泌尿道手术史占比分别为 46.43%、39.29%、39.29%、32.14%、71.43%、50.00%、32.14%,显著高于非血流感染组的 15.15%、19.70%、18.18%、15.91%、38.64%、30.30%、15.15%(P<0.05).经多因素Logistic回归分析显示,有泌尿道手术史、有多重耐药菌感染史、有糖尿病病史、导尿管留置时间≥7 d是尿路感染合并血流感染的危险因素(P<0.05).结论 尿路感染合并血流感染的致病菌多为革兰阴性菌,合并感染发生与糖尿病、多重耐药菌感染、泌尿道手术、导尿管留置时间长密切相关,因此临床应加强尿路感染的风险评估,预测其血流感染发生的可能性,进而早期干预、密切监控,防治血流感染发生.
Analysis of pathogenic bacteria detection and risk factors in patients with urinary tract infection combined with bloodstream infection
Objective To analyze the distribution characteristics of pathogenic bacteria in urine and blood culture samples of patients with urinary tract infection combined with bloodstream infection,and explore the risk factors of concurrent bloodstream infection,and guide clinical development of targeted prevention and treatment measures.Methods The clinical data of 160 patients with urinary tract infection were retrospectively analyzed.The etiological characteristics of urinary tract infection combined with bloodstream infection were analyzed.The general data and relevant data of urinary tract infection were compared between blood stream infection group and non-blood stream infection group,and the risk factors of urinary tract infection with bloodstream infection were analyzed.Results Among 160 patients with urinary tract infection,28 cases(17.50%)were complicated with bloodstream infection.Blood cultures of 28 patients with urinary tract infection and blood stream infections isolated 35 strains of pathogenic bacteria.In blood stream infection group,the percentages of≥80 years of age,absolutely bedridden,diabetes history,primary urinary system disease,Foley catheter retention≥7 d,multi-drug resistant bacteria infection history,and urinary tract surgery history were 46.43%,39.29%,39.29%,32.14%,71.43%,50.00%,and 32.14%,which were significantly higher than 15.15%,19.70%,18.18%,15.91%,38.64%,30.30%,and 15.15%in the non-bloodstream infection group(P<0.05).Multivariate Logistic regression analysis showed that urinary tract surgery history,multi-drug resistant bacteria infection history,diabetes history,and Foley catheter retention≥7 d were risk factors for urinary tract infection combined with bloodstream infection(P<0.05).Conclusion The pathogenic bacteria of urinary tract infection combined with blood flow infection are mostly gram-negative bacteria.The occurrence of combined infection is closely related to diabetes,multi drug resistant bacteria infection,urinary tract surgery,and long Foley catheter retention.Therefore,clinical risk assessment of patients with urinary tract infection should be strengthened,and early intervention and close monitoring should be carried out to prevent blood flow infection.

Urinary tract infectionBloodstream infectionDistribution characteristics of pathogenic bacteriaRisk factors

李艳红、黄佳星、王怡进、梁世炫、刘新凤

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523600 东莞市清溪医院检验科

523600 东莞市清溪医院重症医学科

523600 东莞市清溪医院呼吸与危重症医学科

523600 东莞市清溪医院行政科

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尿路感染 血流感染 病原菌分布特征 危险因素

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20221800904152

2024

中国实用医药
中国康复医学会

中国实用医药

影响因子:0.797
ISSN:1673-7555
年,卷(期):2024.19(18)