Application effect of hypersensitive C-reactive protein and procalcitonin combined with blood routine examination in the diagnosis of infectious diseases in children
Objective To analyze the clinical value of hypersensitive C-reactive protein(hs-CRP)and procalcitonin(PCT)combined with blood routine examination in the diagnosis of infectious diseases in children.Methods 80 cases of children with infectious diseases were selected as study subjects,and they were divided into bacterial infection group(children with bacterial infection,40 cases),non-bacterial infection group(children without bacterial infection,40 cases)according to whether they had bacterial infections or not.Another 40 cases of children who had health checkups were selected as the control group.Venous blood was drawn from all the three groups of children,and the serum was separated by centrifugation.PCT,hs-CRP,and white blood cell count levels were tested and compared among the three groups.Results In the bacterial infection group,the serum PCT was(4.44±1.13)ng/ml,the hs-CRP was(91.52±49.83)mg/L,the white blood cell count was(15.27±5.27)×109/L,which were significantly higher than those in the non-bacterial infection group[(0.44±0.16)ng/ml,(7.41±2.74)mg/L,(9.06±3.78)×109/L]and in the control group[(0.39±0.13)ng/ml,(5.18±2.32)mg/L,(6.70±2.74)×109/L].There was statistical difference(P<0.05).Conclusion hs-CRP and PCT combined blood routine examination have important clinical significance and diagnostic value in the diagnosis of infectious diseases in children.Their application can evaluate the severity of infection,guide the application of antibiotics,monitor the efficacy,assess the prognosis,and provide decision-making support and auxiliary diagnosis.
Infectious diseases in childrenHypersensitive C-reactive proteinProcalcitoninBlood routineDiagnostic value
万方数据
维普
