The value of collecting lesion irrigation fluid for liquid-based cytology instead of brush biopsy in the diagnosis of lung cancer
Objective To explore the value of collecting lesion irrigation fluid for liquid-based cytology instead of brush biopsy in the diagnosis of lung cancer.Methods A total of 120 patients with suspected lung cancer were selected as the study subjects,and 100 patients were diagnosed with lung cancer by mucosal tissue biopsy.All patients underwent brush smear cytology and collected lesion irrigation fluid for liquid-based cytology.Comparison was made on operation time and lesion bleeding after sampling between the two methods,as well as the positivity detection of the two sampling methods in patients confirmed by mucosal tissue biopsy.Results The time taken to collect lesion irrigation liquid was(3.07±0.27)min,which was shorter than(4.27±0.20)min of brush biopsy,and the difference was statistically significant(P<0.05).The bleeding rate of the lesion was 0.83%(1/120)after the collection of lesion irrigation liquid,which was lower than 5.83%(7/120)of brush sampling,and the difference was statistically significant(P<0.05).In 100 cases of patients diagnosed by mucosal tissue biopsy,the positive detection rate of collecting lesion irrigation fluid was 83.00%,which was higher than 59.00%of brushing sampling,and the difference was statistically significant(P<0.05).Conclusion Collecting lesion irrigation fluid for liquid-based cytology instead of brush biopsy has high value in the diagnosis of lung cancer,which can shorten the time taken to collect the sample,reduce the bleeding rate of the lesion after the collection,improve the positive rate of diagnosis,and detect the patient's condition in a timely and accurate manner.
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