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特布他林与布地奈德共同治疗慢阻肺的临床效果及安全性

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目的 观察临床中慢性阻塞性肺疾病(慢阻肺)患者应用特布他林与布地奈德共同治疗的效果.方法 选取 60 例进行呼吸内科诊治的慢阻肺患者,经由随机数字表法分为试验组(30 例)与对照组(30 例).试验组患者以特布他林与布地奈德共同治疗为干预措施,对照组患者以布地奈德治疗为干预措施.对比两组患者治疗效果、不良反应发生率及生活质量评分.结果 治疗后,在治疗总有效率方面,试验组(93.33%)高于对照组(70.00%)(P<0.05).治疗后,在不良反应发生率方面,试验组(3.33%)低于对照组(23.33%)(P<0.05).治疗前,两组心理功能评分、物质生活状态评分及社会功能评分对比,无统计学差异(P>0.05);治疗后,试验组心理功能评分(80.16±4.28)分、物质生活状态评分(81.28±4.61)分、社会功能评分(80.13±3.24)分高于对照组的(71.37±4.64)、(72.13±4.62)、(70.92±3.13)分(P<0.05).结论 特布他林与布地奈德共同治疗用于临床慢阻肺患者医治中,干预效果更好,患者的症状得到较好的缓解,出现不良反应的情况相对更少,且生活质量随之上升,值得被临床应用推广.
Clinical efficacy and safety of combined treatment of terbutaline and budesonide in the treatment of chronic obstructive pulmonary disease
Objective To observe the effect of combined treatment of terbutaline and budesonide in the treatment of patients with chronic obstructive pulmonary disease.Methods 60 patients with chronic obstructive pulmonary disease were selected and divided into an experimental group(30 cases)and a control group(30 cases)by random number table method.The experimental group received combined treatment of terbutaline and budesonide as intervention measures,and the control group received budesonide treatment as intervention measures.The therapeutic effect,incidence of adverse reactions and quality of life score were compared between the two groups.Results After treatment,the total effective rate of the experimental group(93.33%)was higher than that of the control group(70.00%)(P<0.05).After treatment,the incidence of adverse reactions in the experimental group(3.33%)was lower than that in the control group(23.33%)(P<0.05).Before treatment,there were no significant differences in psychological function score,material life status score and social function score between the two groups(P>0.05).After treatment,the experimental group had pychological function score of(80.16±4.28)points,material life status score of(81.28±4.61)points and social function score of(80.13±3.24)points,which were higher than(71.37±4.64),(72.13±4.62)and(70.92±3.13)points in the control group(P<0.05).Conclusion The combined treatment of terbutaline and budesonide in the treatment of clinical chronic obstructive pulmonary disease patients has been shown to be more effective,with better symptomatic relief,fewer adverse effects,and higher quality of life,which is worthy of clinical application.

TerbutalineBudesonideChronic obstructive pulmonary diseaseClinical efficacySecurity

马娟、林立、吕爱爱

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250100 山东省公共卫生临床中心结核内科

特布他林 布地奈德 慢性阻塞性肺疾病 临床效果 安全性

2024

中国实用医药
中国康复医学会

中国实用医药

影响因子:0.797
ISSN:1673-7555
年,卷(期):2024.19(19)