Observation on application effect of Wenjing Decoction in patients with climacteric syndrome of kidney deficiency type
Objective To explore the application effect of Wenjing Decoction in patients with climacteric syndrome of kidney deficiency type.Methods 59 patients with climacteric syndrome of kidney deficiency type were divided into a control group(29 cases)and an observation group(30 cases)by random number table method.The control group received conventional Western medicine treatment,and the observation group was given Wenjing Decoction treatmenton this basis.The clinical efficacy,traditional Chinese medicine syndrome score,reproductive endocrine hormone index level and vegetative nerve functional disturbance adjustment of the two groups were compared.Results The total effective rate of clinical treatment in the observation group was 93.33%,which was higher than 72.41%in the control group(P<0.05).Before treatment,there was no significant difference in the scores and total scores of menstrual disorders,fever and sweating,dysphoria in chestpalms-soles,coldness of the waist and the knee between the two groups(P>0.05).After treatment,the scores and total scores of menstrual disorders,fever and sweating,dysphoria in chestpalms-soles,coldness of the waist and the knee in the observation group were(1.92±0.68),(1.89±0.73),(1.84±0.64),(1.83±0.65)and(7.48±2.61)points,which were lower than(2.36±0.69),(2.43±0.74),(2.24±0.63),(2.19±0.67)and(9.22±2.52)points in the control group(P<0.05).Before treatment,there was no significant difference in estradiol(E2),follicle-stimulating hormone(FSH)and luteinizing hormone(LH)levels between the two groups(P>0.05).After treatment,E2 level of(49.37±3.48)pmol/L in the observation group was higher than(46.89±3.13)pmol/L in the control group;the observation group had FSH level of(33.93±8.67)U/L and LH level of(18.67±3.34)U/L,which were lower than(41.89±8.94)and(21.76±3.09)U/L in the control group(P<0.05).Before treatment,there was no significant difference in the incidence of total vegetative nerve functional disturbance between the two groups(P>0.05).After treatment,the incidence of total vegetative nerve functional disturbance was 6.67%in the observation group,which was lower than 31.03%in the control group(P<0.05).Conclusion The use of Wenjing Decoction in the treatment of climacteric syndrome of kidney deficiency type can regulate the level of patients'reproductive endocrine hormones and vegetative nerve function,alleviate clinical symptoms,and improve the therapeutic effect.
Wenjing DecoctionClimacteric syndrome of kidney deficiency typeReproductive endocrine hormoneVegetative nerve functionTraditional Chinese medicine syndrome score
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