Objective To explore the clinical effect of treating gastroesophageal reflux disease under the concept of"preventive treatment of disease"of traditional Chinese medicine.Methods 68 patients with gastroesophageal reflux disease were divided into a reference group and a study group by coin tossing method,with 34 cases in each group.The reference group was treated with conventional Western medicine,and the study group was treated under the concept of"preventive treatment of disease"of traditional Chinese medicine.Patients in both groups were compared in terms of treatment rate,lifestyle score(regular medication score,healthy diet score,regular rest score and appropriate exercise score),incidence of adverse reactions,relief time of adverse symptoms(belching,acid reflux and stomachache)and traditional Chinese medicine syndrome(belching score,acid reflux score and stomachache score)and gastrointestinal hormone(serum gastrin,motilin,vasoactive intestinal peptide,and substance P)levels.Results The total effective rate of 97.06%in the study group was significantly higher than 76.47%in the reference group(P<0.05).In the study group,the regular medication score was(90.25±2.52)points,the healthy diet score was(91.74±3.15)points,the regular rest score was(90.68±4.22)points and the appropriate exercise score was(91.74±5.25)points,which were significantly higher than(80.33±3.15),(81.22±4.15),(81.22±4.15),(80.28±3.11)and(81.27±4.27)points in the reference group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).The time to remission of belching,acid reflux and stomachache in the study group were(3.25±0.75),(2.19±0.45)and(1.19±0.31)d,which were significantly shorter than(6.63±0.45),(6.96±0.39)and(3.33±0.89)d in the reference group(P<0.05).After treatment,the scores of belching,acid reflux and stomachache in the study group were(2.12±0.25),(2.15±0.33)and(2.16±0.37)points,which were lower than(4.15±0.33),(4.16±0.35)and(4.19±3.12)points in the reference group(P<0.05).After treatment,the study group had serum gastrin of(64.59±5.55)pg/ml,motilin of(263.49±14.61)pg/ml and substance P of(29.75±1.86)pg/ml,which were higher than(55.63±8.95),(210.36±16.85)and(26.49±5.52)pg/ml in the reference group;the vasoactive intestinal peptide of(53.75±7.35)pg/ml in the study group was lower than(58.49±9.81)pg/ml in the reference group(P<0.05).Conclusion The effective application of the concept of"preventive treatment of disease"of traditional Chinese medicine can significantly improve the overall curative effect of patients with gastroesophageal reflux disease,improve the lifestyle,traditional Chinese medicine syndrome and gastrointestinal hormone levels of patients,effectively shorten the time for alleviating adverse symptoms,and will not lead to increased adverse reactions.It is worthy of clinical promotion.
Concept of"preventive treatment of disease"of traditional Chinese medicineGastroesophageal reflux diseaseTherapeutic effectWay of lifeAdverse reactionsDuration of remission of adverse symptomsTraditional Chinese medicine syndrome scoreGastrointestin
万方数据
