Efficacy observation of thoracoscopic thymectomy via two different approaches for anterior mediastinal tumor
Objective To explore the efficacy of thoracoscopic thymectomy via two different approaches for anterior mediastinal tumor.Methods A total of 157 patients with anterior mediastinal tumor were divided into a control group(78 cases)and an observation group(79 cases)according to random number table method.The control group received thoracoscopic thymotomy via intercostal approach,while the observation group received thoracoscopic thymotomy via xiphoid approach.The operation related indexes,inflammation markers and postoperative complications were compared between the two groups.Results In the observation group,the operation time was(72.48±12.32)min and the catheter retention time was(1.32±0.45)d,which were shorter than(98.56±13.45)min and(2.56±0.62)d in the control group;the amount of intraoperative blood loss was(28.56±3.51)ml and the postoperative drainage volume was(192.51±21.35)ml,which were lower than(46.25±6.25)and(265.36±32.51)ml in the control group(P<0.05).1 d before surgery,there were no significant differences in white blood cell count(WBC)and C-reactive protein(CRP)between the two groups(P>0.05).1 d after surgery,WBC and CRP in both groups were higher than those 1 d before surgery;the observation group had WBC of(8.56±1.42)×109/L and CRP of(8.62±1.32)mg/L,which were lower than(10.62±1.51)×109/L and(11.52±1.65)mg/L in the control group(P<0.05).The incidence of postoperative complications in the observation group(5.06%)was lower than that in the control group(15.38%)(P<0.05).Conclusion Compared with thoracoscopic thymectomy via intercostal approach,transxiphoid approach is more helpful to shorten the operation time and catheter retention time of patients with anterior mediastinal tumor,reduce the amount of intraoperative blood loss and postoperative drainage volume,alleviate inflammatory reaction and reduce the occurrence of postoperative complications.