Analysis of application value of combined testing of immunological indicators in the diagnosis of rheumatoid arthritis
Objective To analyze the application value of combined testing of immunological indicators in the diagnosis of rheumatoid arthritis(RA).Methods 150 RA patients were selected as the observation group,and another 150 healthy individuals from the same period of time were selected as the control group.Both groups received combined testing of immunological indicators.Both groups were compared in terms of rheumatoid factor(RF),anti-cyclic citrullinated peptide antibody(anti-CCP antibody),immunoglobulin G(IgG),complement C4 and C3 levels,positive rates of anti-CCP antibody,RF,anti-keratin antibody(AKA),anti-perinuclear factor antibody(APF).Results The observation group had complement C4 of(0.19±0.07)g/L and complement C3 of(0.77±0.23)g/L,which were lower than(0.29±0.10)and(1.05±0.22)g/L in the control group;IgG of(15.27±4.55)g/L in the observation group was higher than(10.71±3.07)g/L in the control group(P<0.05).The anti-CCP antibody of the observation group was(302.58±98.48)IU/ml and RF was(240.13±91.24)IU/ml,which were higher than(6.57±1.23)and(7.25±2.34)IU/ml of the control group(P<0.05).The positive rates of anti-CCP antibody,RF,AKA,and APF of the observation group were 82.67%(124/150),81.33%(122/150),58.67%(88/150),and 18.67%(28/150),which were higher than 0,0.67%(1/150),0,and 0 of the control group(P<0.05).Conclusion Combined testing of immunological indicators has high value in clinical diagnosis of RA.
Anti cyclic citrulline peptide antibodyCombined testing of immunological indicatorsDiagnosisRheumatoid arthritisRheumatoid factor
万方数据
维普
