Distribution characteristics of traditional Chinese medicine syndromes in upper gastrointestinal mucosal lesions caused by Helicobacter pylori infection in children and analysis of the correlation with traditional Chinese medicine constitution
Objective To explore the distribution characteristics of traditional Chinese medicine syndromes in upper gastrointestinal mucosal lesions caused by Helicobacter pylori(Hp)infection in children and analysis of the correlation with traditional Chinese medicine constitution.Methods 230 children diagnosed with upper gastrointestinal mucosal lesions caused by Helicobacter pylori infection were selected as the research subjects.Traditional Chinese medicine syndromes and constitutional identification were carried out according to clinical symptoms and tongue image of the children,and the distribution of traditional Chinese medicine syndromes in different traditional Chinese medicine constitutions of children with upper gastrointestinal mucosal lesions caused by Helicobacter pylori infection was analyzed.Results(i)Among the 230 children,spleen and stomach dampness heat syndrome was the most common,accounting for 25.2%,followed by liver and stomach qi stagnation syndrome,and spleen and stomach qi deficiency syndrome,accounting for 18.7%and 17.4%.There were differences in the percentage of traditional Chinese medicine syndromes,which were spleen and stomach dampness heat syndrome>liver and stomach Qi stagnation syndrome>spleen and stomach Qi deficiency syndrome>stomach Yin deficiency syndrome>spleen and stomach deficiency cold syndrome>liver and stomach stagnation heat syndrome>stomach collateral stasis obstruction syndrome.(ii)Among the 230 children,60 cases were peaceful constitution,accounting for 26.1%.170 cases were biased constitution,accounting for 73.9%.The top 3 biased constitution were damp-heat constitution(21.3%),Qi stagnation constitution(13.0%)and Yin deficiency constitution(11.3%),among which damp-heat constitution was the most common.(iii)Spleen and stomach dampness heat syndrome was the most common in damp-heat constitution,accounting for 44.9%(22/49);liver and stomach qi stagnation syndrome was the most common in Qi stagnation constitution,accounting for 53.3%(16/30);spleen and stomach dampness heat syndrome was the most common in phlegm dampness constitution,accounting for 53.3%(8/15);stomach yin deficiency syndrome was the most common in Yin deficiency constitution,accounting for 65.4%(17/26);spleen and stomach dampness heat syndrome was the most common in peaceful constitution,accounting for 23.3%(14/60).The percentage of spleen and stomach qi deficiency syndrome was 20.0%(12/60),spleen and stomach deficiency cold syndrome was 18.3%(11/60),stomach yin deficiency syndrome was 20.0%(12/60),and liver and stomach qi stagnation syndrome was 13.3%(8/60),which were all higher than 5.0%(3/60)of liver and stomach stagnation heat syndrome.(iv)Liver and stomach qi stagnation syndrome was mainly characterized by Qi stagnation constitution(37.2%,16/43)and peaceful constitution(18.6%,8/43);spleen and stomach dampness heat syndrome was mainly characterized by dampness-heat constitution(37.9%,22/58),peaceful constitution(24.1%,14/58)and phlegm-dampness constitution(13.8%,8/58);spleen and stomach Qi deficiency syndrome was mainly characterized by Qi deficiency constitution(30.0%,12/40)and peaceful constitution(30.0%,12/40).Conclusion Hp infection induced upper gastrointestinal mucosal lesions are more common in children with biased constitution,mainly characterized by damp heat constitution,Qi stagnation constitution,and Yin deficiency constitution.Combined with the adjustability of constitution,correcting or improving biasd constitution can improve the clinical symptoms of the disease and play a preventive role.
Helicobacter pyloriUpper gastrointestinal mucosal lesionsTraditional Chinese medicine constitutionTraditional Chinese medicine syndromes
万方数据
维普
