中国实用医药2024,Vol.19Issue(20) :152-155.DOI:10.14163/j.cnki.11-5547/r.2024.20.041

厚朴排气合剂联合莫沙必利治疗原发性胆汁反流性胃炎的临床疗效分析

Analysis of clinical efficacy of Houpo Paiqi mixture combined with mosapride in the treatment of primary bile reflux gastritis

廖山婴 黄霖琳 王蓓蓓 卢勉芬 郭映玲 布小玲
中国实用医药2024,Vol.19Issue(20) :152-155.DOI:10.14163/j.cnki.11-5547/r.2024.20.041

厚朴排气合剂联合莫沙必利治疗原发性胆汁反流性胃炎的临床疗效分析

Analysis of clinical efficacy of Houpo Paiqi mixture combined with mosapride in the treatment of primary bile reflux gastritis

廖山婴 1黄霖琳 1王蓓蓓 1卢勉芬 1郭映玲 1布小玲1
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作者信息

  • 1. 510080 南方医科大学附属广东省人民医院,广东省医学科学院消化内科
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摘要

目的 探讨厚朴排气合剂联合莫沙必利治疗原发性胆汁反流性胃炎的临床效果.方法 160 例原发性胆汁反流性胃炎患者,用随机数字表法分为对照组和研究组,每组 80 例.对照组应用莫沙必利治疗,研究组应用莫沙必利联合厚朴排气合剂治疗.比较两组患者临床疗效、胃镜下疗效及胃电节律、不良反应发生情况.结果 研究组患者临床总有效率 96.25%高于对照组的 85.00%,差异有统计学意义(P<0.05).研究组患者胃镜下总有效率 95.00%高于对照组的 78.75%,差异有统计学意义(P<0.05).治疗后,两组患者胃窦、胃体餐后餐前主功率比值均高于本组治疗前,且研究组患者胃窦、胃体餐后餐前主功率比值分别为(1.31±0.22)、(1.29±0.20),高于对照组的(1.17±0.16)、(1.18±0.15),差异有统计学意义(P<0.05).两组患者不良反应发生率比较差异无统计学意义(P>0.05).结论 应用莫沙必利联合厚朴排气合剂治疗原发性胆汁反流性胃炎患者效果十分显著,值得推广应用.

Abstract

Objective To explore the clinical effect of Houpo Paiqi mixture combined with mosapride in the treatment of primary bile reflux gastritis.Methods 160 patients with primary bile reflux gastritis were divided into a control group and a study group by random number table method,with 80 cases in each group.The control group was treated with mosapride,and the study group was treated with mosapride combined with Houpo Paiqi mixture.The clinical efficacy,efficacy under gastroscope,gastric electric rhythm and the occurrence of adverse reactions between the two groups.Results The total clinical effective rate of 96.25%in the study group was higher than 85.00%in the control group,and the difference was statistically significant(P<0.05).The total effective rate under gastroscopy in the study group was 95.00%,which was higher than 78.75%in the control group,and the difference was statistically significant(P<0.05).After treatment,the postprandial and preprandial main power ratios of the gastric sinus and gastric body in both groups were higher than those before treatment in this group;the postprandial and preprandial power ratios of the gastric sinus and gastric body were(1.31±0.22)and(1.29±0.20)in the study group,which were higher than(1.17±0.16)and(1.18±0.15)in the control group;the difference was statistically significant(P<0.05).The difference in the incidence of adverse reactions between the two groups was not statistically significant(P>0.05).Conclusion The application of mosapride combined with Houpo Paiqi mixture has a very significant effect in the treatment of patients with primary bile reflux gastritis,and is worthy of popularization and application.

关键词

原发性胆汁反流性胃炎/厚朴排气合剂/莫沙必利/疗效/胃电节律

Key words

Primary bile reflux gastritis/Houpo Paiqi mixture/Mosapride/Efficacy/Gastric electric rhythm

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出版年

2024
中国实用医药
中国康复医学会

中国实用医药

影响因子:0.797
ISSN:1673-7555
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