Study on clinical efficacy of Xiao'er Yiqi Granule in treating children with Qi-deficiency type of constipation
Objective To analyze the clinical efficacy of Xiao'er Yiqi Granule in treating children with Qi-deficiency type of constipation.Methods A total of 70 children with Qi-deficiency type of constipation were selected.They were divided into a control group and a treatment group by envelope method,with 35 cases in each group.The children in the control group were treated with compound eosinophil-lactobacillus tablets,and the children in the treatment group were treated with Xiao'er Yiqi Granules.The therapeutic effect,degree of constipation,traditional Chinese medicine syndrome score,serum substance P,vasoactive intestinal peptide and the occurrence of adverse reactions were compared between the two groups.Results After 2 weeks of treatment,the score of degree of constipation,traditional Chinese medicine syndrome score,serum substance P and vasoactive intestinal peptide were improved in both groups compared with those before treatment;in the treatment group,the score of degree of constipation was(3.56±0.46)points,the traditional Chinese medicine syndrome score was(18.19±2.35)points,the serum substance P was(63.56±10.46)ng/L,and the vasoactive intestinal peptide was(11.12±2.35)ng/L,which were significantly better than(2.52±0.45)points,(21.14±2.12)points,(38.21±6.48)ng/L,and(14.67±2.88)ng/L in the control group(P<0.05).The total effective rate of the treatment group(94.29%)was higher than that of the control group(74.29%)(P<0.05).The incidence of adverse reactions of 0 in the treatment group was lower than 17.14%in the control group(P<0.05).Conclusion Xiao'er Yiqi Granule has a better therapeutic effect,safety,and effectiveness in treating children's constipation compared to Western medicine.
Xiao'er Yiqi GranuleQi-deficiency typeConstipation in childrenClinical efficacy
万方数据
维普
