Evaluation of the effect of bone resorption inhibitors in the treatment of osteoporosis
Objective To explore the effect of bone resorption inhibitors in the treatment of osteoporosis.Methods 60 patients with OP were randomly divided into an observation group(calcium carbonate D3 tablets+sodium ibandronate injection)and a control group(calcium carbonate D3 tablets),each with 30 cases.Both groups were compared in terms of bone mineral density,rehabilitation indicators[scores of Oswestry Disability Index(ODI),Visual Analogue Scale(VAS),Morse Fall Scale(MFS)and Berg Balance Scale(BSS),time required to walk 6 m]and quality of life.Results After treatment,the bone density of lumbar spine and hip in the observation group was greater than that of the control group(P<0.05).After treatment,the ODI score in the observation group was(31.01±2.60)points,the BSS score was(54.61±3.17)points,the time required to walk 6 m was(7.95±0.64)s,the MFS score was(40.24±2.17)points,and the VAS score was(2.85±0.44)points;in the control group,the ODI score was(37.68±5.47)points,the BSS score was(49.24±8.44)points,the time required to walk 6 m was(8.96±0.77)s,the MFS score was(45.20±6.77)points,and the VAS score was(3.19±0.65)points.After treatment,the ODI score,MFS score,and VAS score of the observation group were lower than those of the control group,the BSS score was higher than that of the control group,and the time required to walk 6 m was shorter than that of the control group(P<0.05).After treatment,the scores of social functioning,role-emotional,role-physical,and vitality of the observation group were higher than those of the control group(P<0.05).Conclusion Bone resorption inhibitors can effectively improve bone density and enhance efficacy in the treatment of steoporosis,with high clinical application value.
OsteoporosisBone resorption inhibitorsBone densityRehabilitation indicatorsQuality of life
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