Effectiveness analysis of Yuanhu Zhitong Capsule in treating knee osteoarthritis
Objective To study the effect of Yuanhu Zhitong Capsule in treating knee osteoarthritis.Methods 89 patients with knee osteoarthritis were assigned into the conventional group(45 cases)and the experimental group(44 cases)according to odd even numbers.Patients in the conventional group were treated with diclofenac sodium,while patients in the experimental group were treated with Yuanhu Zhitong Capsules.The pain,knee range of motion,knee function score and adverse drug reactions were compared between the two groups.Results After 7 and 15 d of treatment,the pain scores of the experimental group were(4.19±0.21)and(1.12±0.35)points,which were lower than(5.02±0.58)and(3.18±0.26)points of the conventional group;the pain duration of the experimental group were(2.90±0.14)and(0.52±0.11)h/d,which were shorter than(3.25±0.25)and(1.71±0.30)h/d of the conventional group;the difference was significant(P<0.05).After 7 and 15 d of treatment,the knee flexion of the experimental group were(70.48±2.19)and(93.60±4.25)°,and the knee extension were(13.58±1.43)and(15.67±0.94)°,which were greater than(52.69±7.43),(87.60±5.42)° and(11.18±1.60),(13.90±1.28)° in the conventional group,and the differences were significant(P<0.05).After treatment,the knee function score of the experimental group was(80.56±1.95)points,which was higher tha(74.25±2.60)n points of the conventional group,and the difference was significant(P<0.05).The incidence rate of adverse reactions was 4.55%(2/44)in the experimental group,which was lower than 20.00%(9/45)in the conventional group,and the difference was significant(P<0.05).Conclusion Yuanhu Zhitong Capsule is safe to use in the treatment of knee osteoarthritis,which can significantly alleviate limb pain,improve knee range of motion and motor function with high safety profile.
Yuanhu Zhitong CapsuleKnee osteoarthritisDiclofenac sodiumKnee joint movement function
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