Study on the efficacy of modified Shenling Baizhu Powder in the treatment of tumor patients and its influence on their quality of life
Objective To study and analyze the efficacy of modified Shenling Baizhu Powder in the treatment of tumor patients and its influence on their quality of life. Methods 114 cases of tumor patients were selected and randomly divided into a control group and an observation group,each with 57 cases. The control group was given conventional treatment with Western medicine,and the observation group was combined with modified Shenling Baizhu Powder on the basis of the control group. Both groups were compared in terms of clinical efficacy,quality of life[36-Item Short-Form Health survey (SF-36) and quality of life scale (QOL) scores],immune function indicators[cytotoxic T cells (Tc),regulatory T cells (Treg),suppressor T cells (Ts),and natural killer (NK) cells],and Karnorfsky's performance scale (KPS) score after treatment. Results Compared with 49.12％ and 68.42％ in the control group,the observation group's treatment efficiency of 73.68％ and tumor control rate of 87.72％ were significantly higher after treatment (P<0.05). Before treatment,there was no statistically significant difference in SF-36 and QOL scores between the two groups (P>0.05). After treatment,the SF-36 and QOL scores in both groups were significantly higher than those before treatment;the SF-36 and QOL scores were (91.94±5.72) and (51.02±3.47) points in the observation group,which were significantly higher than (84.62±4.22) and (42.49±3.16) points in the control group (P<0.05). Before treatment,there was no significant difference in Tc,Treg,Ts and NK levels between the two groups (P>0.05). After treatment,NK and Tc levels in both groups were significantly higher than those before treatment,and Treg and Ts levels were significantly lower than those before treatment;the observation group had NK of (22.61±3.03)％ and Tc of (15.67±2.63)％,which were significantly higher than (18.82±2.59)％ and (13.26±1.73)％ in the control group;the observation group had Treg of (5.02±0.29)％ and Ts of (14.04±2.30)％,which were significantly lower than (6.97±1.00)％ and (16.92±3.27)％ in the control group (P<0.05). Before treatment,the KPS scores of the observation group and the control group were (66.35±13.65) and (64.58±14.85) points,and there was no statistical significance between the two groups (P>0.05). After treatment,the KPS score of the observation group was (84.12±14.77) points,and that of the control group was (72.67±12.48) points;the KPS score of the two groups was higher than that before treatment,and the observation group had significantly higher KPS score than that of the control group (P<0.05). Conclusion Modified Shenling Baizhu Powder in the treatment of tumor patients can significantly improve its clinical efficacy,improve the immune function of the body,and enhance the quality of life of patients.
Shenling Baizhu PowderTumorEfficacyQuality of life
万方数据
维普
