The effect of nerve-oriented total mesorectal excision on postoperative sexual function in patients with rectal cancer
Objective To explore the effect of nerve-oriented total mesorectal excision (TME) on postoperative sexual function in patients with rectal cancer. Methods 82 male patients with rectal cancer were selected and divided into an observation group and a control group using a random number table method,with 41 cases in each group. The observation group was treated with nerve-oriented TME,and the control group was treated with TME. The score of International Index of Erectile Function-5 (IIEF-5),ejaculatory function and erectile function grading,urination function grading,incidence of complications and postoperative recurrence were compared between the two groups. Results The IIEF-5 scores of the observation group were (23.35±1.43),(20.25±2.39) and (18.42±2.31) points before surgery and 3 and 6 months after surgery,while those of the control group were (23.42±1.62),(17.50±2.75) and (15.53±2.82) points. At 3 and 6 months after surgery,the IIEF-5 scores in both groups were lower than those before surgery,but IIEF-5 score in the observation group was higher than that in the control group,and the difference was statistically significant (P<0.05). The observation group had 35 cases (85.37％) of erectile function grade Ⅰ,5 cases (12.20％) of grade Ⅱ,and 1 case (2.44％) of grade Ⅲ,while the control group had 26 cases (63.41％) of grade Ⅰ,12 cases (29.27％) of grade Ⅱ,and 3 cases (7.32％) of grade Ⅲ. The observation group had 28 cases (68.29％) of ejaculatory function grade Ⅰ,11 cases (26.83％) of grade Ⅱ,and 2 cases (4.88％) of grade Ⅲ,while the control group had 14 cases (34.15％) of grade Ⅰ,16 cases (39.02％) of grade Ⅱ,and 11 cases (26.83％) of grade Ⅲ. The erectile function grading as well as ejaculatory function grading of the observation group was better than those of the control group,and the difference was statistically significant (P<0.05). The observation group had 29 cases (70.73％) of urination function grade Ⅰ,7 cases (17.07％)of grade Ⅱ,4 cases (9.76％) of grade Ⅲ and 1 case (2.44％) of grade Ⅳ,while the control group had 16 cases (39.02％) of grade Ⅰ,15 cases (36.59％) of grade Ⅱ,7 cases (17.07％) of grade Ⅲ and 3 cases (7.32％) of grade Ⅳ. The urination function grading of the observation group was better than that of the control group,and the difference was statistically significant (P<0.05). The incidence of complications in the observation group was 4.88％ (2/41) and the postoperative recurrence rate was 2.44％ (1/41),and the difference was not statistically significant when compared with the control group[9.76％ (4/41) and 7.32％ (3/41)](P>0.05). Conclusion Nerve-oriented TME therapy is effective in patients with rectal cancer,and has little effect on patients' genitourinary function,and has certain safety.
万方数据
维普
