Clinical effect analysis of mifepristone combined with misoprostol in early abortion
Objective To explore the effect of mifepristone combined with misoprostol in early abortion. Methods 90 patients with early abortion were randomly divided into a control group and an observation group,with 45 cases in each group. The control group was treated with painless abortion,and the observation group was treated with mifepristone tablets combined with misoprostol before painless abortion. The effect of cervical dilation,intraoperative and postoperative indicators and the occurrence of induced abortion syndrome were compared between the two groups. Results The total effective rate of cervical dilation was 97.78％ in the observation group,which was significantly higher than 82.22％ in the control group (P<0.05). The duration of postoperative vaginal bleeding and total operation time were (4.68±1.56) d and (4.05±0.86) min in the observation group,which were shorter than (6.90±2.37) d and (5.31±1.18) min in the control group;the intraoperative blood loss and total anesthetic dose were (5.31±1.18) and (14.47±2.25) ml in the observation group,which were lower than (42.27±13.70) and (18.50±5.13) ml in the control group (P<0.05). The incidence of induced abortion syndrome was 6.67％ in the observation group,which lower than 22.22％ in the control group (P<0.05). Conclusion For patients with early abortion,the implementation of mifepristone combined with misoprostol before painless abortion can enhance the cervical dilatation of patients,reduce the total operation time and intraoperative blood loss,improve the safety of treatment,and facilitate rapid prognosis,which is worthy of reference.
万方数据
维普
