Clinical observation on the treatment of chronic obstructive pulmonary disease with phlegm dampness accumulation syndrome by modified Erchen Decoction and Suzi Jiangqi Decoction combined with acupoint thread-embedding
Objective To explore the clinical efficacy of modified Erchen Decoction and Suzi Jiangqi Decoction combined with acupoint thread-embedding in the treatment of chronic obstructive pulmonary disease (COPD) with phlegm dampness accumulation syndrome. Methods 300 cases of COPD with phlegm dampness accumulation syndrome were selected as the research subjects. According to the random number table method,they were divided into an observation group (n=150) and a control group (n=150). The patients of the control group received conventional therapy,while the patients of the observation group were treated with modified Erchen Decoction and Suzi Jiangqi Decoction combined with acupoint thread-embedding on the basis of the conventional therapy. Both groups were compared in terms of traditional Chinese medicine syndrome score (cough,wheezing,chest tightness),blood gas indicators[arterial partial pressure of carbon dioxide (PaCO2),arterial partial pressure of oxygen (PaO2)],and lung function indicators[forced expiratory volume in one second (FEV1),forced vital capacity (FVC),peak expiratory flow (PEF)]before and after treatment,and clinical efficacy. Results The total effective rate of 93.33％ in the observation group was significantly higher than 73.33％ in the control group (P<0.05). After treatment,the traditional Chinese medicine syndrome scores in both groups decreased significantly compared with those before treatment;the scores of cough,wheezing and chest tightness were (0.80±0.09),(1.02±0.13) and (0.19±0.15) points in the observation group,which were significantly lower than (1.32±0.14),(2.10±0.22) and (0.70±0.08) points in the control group;the difference was significant (P<0.05). After treatment,the PaO2 and PaCO2 of the observation group were (80.46±8.12) and (35.28±3.61) mm Hg (1 mm Hg=0.133 kPa),and those of the control group were (69.11±7.01) and (44.86±4.60) mm Hg. Compared with before treatment,PaCO2 was significantly decreased and PaO2 was significantly increased in both groups after treatment;compared with the control group,the observation group had lower PaCO2 and higher PaO2;the difference was significant (P<0.05). Compared with before treatment,FEV1,FVC and PEF were significantly increased in both groups after treatment;the observation group had FEV1 of (3.21±0.33) L,PEF of (455.12±46.10) L/min and FVC of (3.61±0.37) L,which were significantly higher than (2.32±0.23) L,(398.25±40.28) L/min and (3.06±0.31) L in the control group;the difference was significant (P<0.05). Conclusion Modified Erchen Decoction and Suzi Jiangqi Decoction combined with acupoint thread-embedding has significant clinical efficacy in COPD patients with phlegm dampness accumulation syndrome,and is worthy of clinical application.
万方数据
维普
